| Type | Description |
|---|---|
| Definition | Amyloid-beta-like protein |
| Date | Results | Publications |
|---|---|---|
| 2014-08-16 11:51:00 | Data indicate that APL1-D2 binds Cu(I) and Cu(II) too weakly to sustain catalysis which suggests that it plays no significant role in copper handling in C. elegans. | 24276282 |
| 2013-08-31 12:13:00 | present hypothetical models as to how sAPL-1 signaling influences metabolic and developmental pathways. | 23044509 |
| 2012-12-22 10:44:00 | [review] Either loss or overexpression of APL-1 will result in lethality, demonstrating the importance of maintaining APL-1 within homeostatic levels, particularly within neurons. | 22038715 |
| 2012-11-03 11:09:00 | Pan-neuronal expression of APL-1, the Caenorhabditis elegans ortholog of APP, disrupts several behaviors, such as olfactory and gustatory learning behavior and touch habituation. | 22836251 |
| 2012-10-27 10:58:00 | signaling of the released APL-1 fragment modulates multiple metabolic states and that APL-1 is required throughout development. | 22466039 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
A4_CAEEL
UniprotKB:
Q10651
UniParc:
UPI0000125044,
UPI000002A2EF
EMBL:
FO080659,
U00240
EnsemblGenome:
WBGene00000149
KO:
cel:CELE_C42D8.8
|
| Nucleutide sequences |
EMBL-CDS:
CCD65568.1,
AAC46470.1,
CCD65569.1
Gene_ORFName:
C42D8.8
EnsemblGenome_TRS:
C42D8.8a.1,
C42D8.8b.1
|
| Protein sequencees |
EnsemblGenome_PRO:
C42D8.8b.1,
C42D8.8a.1
RefSeq:
NP_508871.1,
NP_508870.3
|
| Others |
UniRef100:
UniRef100_Q10651
UniRef90:
UniRef90_Q10651
UniRef50:
UniRef50_Q10651
UniGene:
Cel.6164
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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