| Type | Description |
|---|---|
| Definition | Hypoxia-inducible factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-15 10:53:00 | The rhy-1 gene encodes a predicated O-acyltransferase enzyme that has previously been shown to negatively regulate HIF-1 activity. Our data indicate that RHY-1 has novel, hif-1 independent, function that promotes survival in H2S. | 31371406 |
| 2019-03-30 11:55:00 | The authors discovered that a HIF target, the Caenorhabditis elegans gene cyp-36A1, is required for numerous HIF-dependent processes, including modulation of gene expression, stress resistance, and behavior. | 30010540 |
| 2017-12-16 12:05:00 | Our results suggest that these detoxification pathways are mediated by the hypoxia inducible factor HIF-1. Finally, we show that sulfide resistance varies among wild C. elegans and other nematode species, suggesting that tolerance to sulfide was naturally selected in certain habitats. | 28179109 |
| 2017-06-03 10:49:00 | blocking HIF-1 activity may promote survival in cells with compromised mitochondrial function. | 27618966 |
| 2016-06-11 11:55:00 | HIF-1-mediated activation of 5-HT signalling promotes axon regeneration by activating both the RhoA and cAMP pathways. | 26790951 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
HIF1_CAEEL,
A0A0K3AXG6_CAEEL
UniprotKB:
G5EGD2,
A0A0K3AXG6
UniParc:
UPI00017172E6,
UPI000228F5D4,
UPI0006454616,
UPI00004EC110,
UPI00000860A7,
UPI000007AEC4
EMBL:
AF364604,
AL023842,
BX284605,
Z92833
EnsemblGenome:
WBGene00001851
KO:
cel:CELE_F38A6.3
|
| Nucleutide sequences |
EMBL-CDS:
CAB07380.2,
CAD54167.1,
AAK62778.1,
CAD54141.2,
CAB07381.2,
CCD31074.1,
CTQ86693.1
Gene_ORFName:
F38A6.3,
F38A6.3,
CELE_F38A6.3
EnsemblGenome_TRS:
F38A6.3b.1,
F38A6.3d.1,
F38A6.3c.1,
F38A6.3a.1,
F38A6.3e.1
|
| Protein sequencees |
EnsemblGenome_PRO:
F38A6.3c.1,
F38A6.3b.1,
F38A6.3d.1,
F38A6.3e.1,
F38A6.3a.1
RefSeq:
NP_001023892.1,
NP_508008.4,
NP_001359648.1,
NP_001023891.2,
NP_001023894.2,
NP_001299994.1
|
| Others |
UniRef100:
UniRef100_G5EGD2-2,
UniRef100_G5EGD2
UniRef90:
UniRef90_G5EGD2
UniRef50:
UniRef50_G5EGD2
UniGene:
Cel.17085
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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