| Type | Description |
|---|---|
| Definition | nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-05 13:53:00 | NF-kappaB2 signalling in enteroids modulates enterocyte responses to secreted factors from bone marrow-derived dendritic cells. | 31772152 |
| 2020-05-23 10:47:00 | Gene expression and chromatin accessibility analyses of in vivo- and ex vivo-generated LSD1-deficient MZB indicated that LSD1 regulated the downstream target genes of noncanonical NF-kappaB signaling. Additionally LSD1 was found to interact with the noncanonical NF-kappaB transcription factor p52. | 31492745 |
| 2020-01-11 10:52:00 | Inactivation of NF-kappaB2 (p52) restrains hepatic glucagon response via preserving PDE4B induction. | 31541100 |
| 2019-10-12 11:01:00 | The study investigated the impact of non-canonical NF-kappaB signaling on lung carcinogenesis. p52 over-expression led to increased tumor number and progression after injection of the carcinogen urethane in mice. Gene expression analysis of lungs from transgenic mice combined with in vitro studies suggested that p52 promotes proliferation of lung epithelial cells through regulation of cell cycle-associated genes. | 29666445 |
| 2018-10-13 12:10:00 | in vivo bioluminescence imaging in a transgenic model of inflammation showed that luciferase activity coincided with endogenous p52/p100 Nfkb2 expression | 29680659 |
| Type | IDs |
|---|---|
| Synonymous | NF-kappaB2, lyt, p49, p49/p100, p50B, p52 |
| Gene |
UniProtKB-ID:
NFKB2_MOUSE,
Q3UV15_MOUSE,
Q3UG25_MOUSE
UniprotKB:
Q9WTK5,
Q3UV15,
Q3UG25
UniParc:
UPI00005ABDAC,
UPI0000028BC4
EMBL:
AF155373,
BC027423,
AK150012,
AK148160,
AK137680,
AK144994,
AF155372,
AF135125
Ensembl:
ENSMUSG00000025225
KO:
mmu:18034
|
| Nucleutide sequences |
EMBL-CDS:
AAH27423.1,
AAD39546.1,
AAD39547.1,
AAD39462.1,
BAE23458.1,
BAE26174.1,
BAE28384.1,
BAE29237.1
Ensembl_TRS:
ENSMUST00000073116,
ENSMUST00000111881,
ENSMUST00000236591
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000107512,
ENSMUSP00000157542,
ENSMUSP00000072859
RefSeq:
XP_006526806.1,
NP_001170840.1,
NP_001170841.1,
NP_062281.1
|
| Others |
UniRef100:
UniRef100_Q3UV15,
UniRef100_Q9WTK5
UniRef90:
UniRef90_Q9WTK5
UniRef50:
UniRef50_Q9WTK5
UniGene:
Mm.102365
CCDS:
CCDS29874.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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