| Type | Description |
|---|---|
| Definition | Spindle assembly abnormal protein 5 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-09 12:43:00 | The interdependence of SAS-5 oligomerization and microtubule binding reflects an avidity mechanism, which also strengthens SAS-5 associations with other centriole components and, thus, promotes organelle assembly. | 29367435 |
| 2018-07-21 11:54:00 | Our data suggest that the APC/C(FZR-1) regulates SAS-5 levels by directly recognizing the conserved KEN-box motif, contributing to proper centrosome duplication. Together, our work shows that FZR-1 plays a conserved role in regulating centrosome duplication in C. elegans | 29030390 |
| 2016-03-12 10:18:00 | Disruption of either domain leads to centriole duplication failure in worm embryos, indicating that large SAS-5 assemblies are necessary for function in vivo. | 26023830 |
| 2013-02-09 10:58:00 | It was demonstrated that the short SAS-5 C-terminal domain (residues 390-404) specifically binds to a narrow central region (residues 275-288) of the SAS-6 coiled coil. | 23064147 |
| 2010-01-21 00:00:00 | SAS-5 has a role in nuclear morphology in Caenorhabditis elegans | 15724817 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SAS5_CAEEL
UniprotKB:
Q20010
UniParc:
UPI00001793E8,
UPI0000082528
EMBL:
Z74032
EnsemblGenome:
WBGene00009385
KO:
cel:CELE_F35B12.5
|
| Nucleutide sequences |
EMBL-CDS:
CCD31072.1,
CAA98463.2
Gene_ORFName:
F35B12.5
EnsemblGenome_TRS:
F35B12.5c.2,
F35B12.5a.1,
F35B12.5a.2,
F35B12.5c.1
|
| Protein sequencees |
EnsemblGenome_PRO:
F35B12.5c.2,
F35B12.5c.1,
F35B12.5a.2,
F35B12.5a.1
RefSeq:
NP_001256338.1,
NP_001256339.1
|
| Others |
UniRef100:
UniRef100_Q20010
UniRef90:
UniRef90_Q20010
UniRef50:
UniRef50_Q20010
UniGene:
Cel.3763
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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