| Type | Description |
|---|---|
| Definition | myosin, heavy polypeptide 4, skeletal muscle |
| Date | Results | Publications |
|---|---|---|
| 2014-07-12 12:49:00 | C-to-T SNP in a 708-bp intron is responsible for the mini-muscle phenotype, Myh4Minimsc. | 24056412 |
| 2013-11-02 10:05:00 | A detailed functional study of muscle fibers from Myh4(arl) mice, which carry a mutation that provokes an L342Q change within the catalytic domain of the type IIb skeletal muscle myosin protein MYH4, is reported. | 23335206 |
| 2012-06-23 10:39:00 | study describes the identification of a recessive missense mutation in the Myh4 gene and its consequences at cellular, physiological and pathological level in the ariel mouse; findings suggest that ariel suffers from a fulminant myofibrillar myopathy | 22199023 |
| 2010-01-21 00:00:00 | In myotonic fast muscles, hyperexcitability leads to a drastic reduction of MyHC IIB which is compensated by IIA. MyHC pattern of of spinal muscular atrophy (SMA) 'wobbler' mice is shifted to a faster phenotype, with nearly 90% IIB | 15013776 |
| 2010-01-21 00:00:00 | MHC2B, together with myosin light chain phosphorylation and actin, constitute the actomyosin cytoskeleton that mediates contractility during apoptosis. | 18445680 |
| Type | IDs |
|---|---|
| Synonymous | AI506973, MHC2B, MM, MYH-2B, Minimsc, Minmus, MyHC-IIb, Myhsf |
| Gene |
UniProtKB-ID:
MYH4_MOUSE,
Q3UUB1_MOUSE
UniprotKB:
Q5SX39,
Q3UUB1
UniParc:
UPI000047046F,
UPI00005ABE47
EMBL:
AK138608,
BC141362,
AL596129
Ensembl:
ENSMUSG00000057003
KO:
mmu:17884
|
| Nucleutide sequences |
EMBL-CDS:
AAI41363.1,
BAE23716.1
Ensembl_TRS:
ENSMUST00000018632,
ENSMUST00000170942
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000018632,
ENSMUSP00000127514
RefSeq:
NP_034985.2
|
| Others |
UniRef100:
UniRef100_Q5SX39
UniRef90:
UniRef90_Q5SX39
UniRef50:
UniRef50_P13535
UniGene:
Mm.297382,
Mm.340163
CCDS:
CCDS24856.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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