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178250 mbk-2

178250

mbk-2

Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2

研究结论

Date Results Publications
2021-03-20 13:27:00 Phosphorylation of the microtubule-severing AAA+ enzyme Katanin regulates C. elegans embryo development. 32412594
2010-10-23 10:43:00 Phosphorylation by MBK-2 facilitates the binding of OMA proteins to TAF-4 and simultaneously inactivates their function in repressing zif-1 translation during the specification of primordial germ cells. 20826530
2010-01-21 00:00:00 MBK-2 phosphorylates OMA-1 in vitro, primarily at threonine239; phosphorylation at T239 is required both for OMA-1 function in the 1-cell embryo and its degradation after the first mitosis 16289132
2010-01-21 00:00:00 The pseudotyrosine phosphatases EGG-4 and EGG-5 sequester activated MBK-2 until the meiotic divisions by binding to the YTY motif and inhibiting MBK-2's kinase activity directly. 19879842
2010-01-21 00:00:00 MBK-2 down-regulates the katanin-related protein MEI-1 to control spindle positioning and, through yet unknown factors, to control the localization of cytoplasmic determinants. 14697358

名称对应

Type IDs
Gene
UniProtKB-ID: MBK2_CAEEL, A0A061AKR6_CAEEL, A0A061ACK4_CAEEL, A0A061AJ20_CAEEL, A0A061ACN7_CAEEL
UniprotKB: Q9XTF3, A0A061AKR6, A0A061ACK4, A0A061AJ20, A0A061ACN7
UniParc: UPI0002537AE3, UPI00049AEA3F, UPI00006975AD, UPI000005ECAF, UPI0000482B90, UPI000499F510, UPI00006C5D05, UPI0000074E9A, UPI0000077BBC, UPI0002537AE2, UPI00049A05F0, UPI00027F1C9F
EMBL: Z81146, Z70308, Z81121, AY090019, BX284604
EnsemblGenome: WBGene00003150
KO: cel:CELE_F49E11.1
Nucleutide sequences
EMBL-CDS: CAB54254.2, CCM09396.1, CAJ76942.1, CCG28134.1, CAA94352.1, CCG28133.1, AAM09088.1, CAA94353.1, CAJ80814.1, CDR32681.1, CDR32679.1, CDR32680.1, CDR32682.1
Gene_ORFName: F49E11.1, F49E11.1, CELE_F49E11.1, F49E11.1, CELE_F49E11.1, CELE_F49E11.1, F49E11.1, F49E11.1, CELE_F49E11.1
EnsemblGenome_TRS: F49E11.1b.1, F49E11.1e.1, F49E11.1d.1, F49E11.1a.1, F49E11.1h.1, F49E11.1f.1, F49E11.1d.2, F49E11.1c.1, F49E11.1d.3, F49E11.1g.1
Protein sequencees
EnsemblGenome_PRO: F49E11.1c.1, F49E11.1d.3, F49E11.1g.1, F49E11.1h.1, F49E11.1f.1, F49E11.1d.2, F49E11.1a.1, F49E11.1b.1, F49E11.1e.1, F49E11.1d.1
RefSeq: NP_001293916.1, NP_001293915.1, NP_001368149.1, NP_001293914.1, NP_001368473.1, NP_001366773.1, NP_001293917.1, NP_001368474.1, NP_001368118.1, NP_001040951.1, NP_001040950.1, NP_001023207.1, NP_001255695.1, NP_001023208.1
Others
UniRef100: UniRef100_Q9XTF3, UniRef100_Q9XTF3-7, UniRef100_A0A061ACN3
UniRef90: UniRef90_Q9XTF3-2, UniRef90_Q9XTF3
UniRef50: UniRef50_Q9XTF3, UniRef50_Q9XTF3-2
UniGene: Cel.7508, Cel.39641

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