| Type | Description |
|---|---|
| Definition | methylenetetrahydrofolate reductase |
| Date | Results | Publications |
|---|---|---|
| 2019-03-23 12:21:00 | Maternal and offspring Mthfr genotypes interact in a mouse model to induce autism spectrum disorder-like behavior. | 30552741 |
| 2019-03-09 10:21:00 | The data suggest that MTHFR deficiency decreases recovery after stroke by reducing neuronal and astrocyte viability. | 30055159 |
| 2019-02-02 12:04:00 | data provide evidence for a similar cross-species response to high dose folic acid supplementation, of sperm DNA hypomethylation, and implicate MTHFR downregulation as a possible mechanism. | 29360980 |
| 2018-02-17 10:32:00 | findings indicate that the loss of folate as a methyl donor is a modifier of allergic airway disease, and that epigenetic and expression changes correlate with this modification. | 29329322 |
| 2017-07-01 11:33:00 | Ganglion cell loss and vasculopathy observed in Mthfr+/- and Cbs+/- mouse retinas may be milder than expected, not because of compensatory increases of enzymes in remethylation/transsulfuration pathways, but because downstream transsulfuration pathway products GSH, taurine, and H2S are maintained at robust levels. | 28384716 |
| Type | IDs |
|---|---|
| Synonymous | AI323986 |
| Gene |
UniProtKB-ID:
MTHR_MOUSE,
A2A7F7_MOUSE,
Q3UDB2_MOUSE,
Q497H7_MOUSE
UniprotKB:
Q9WU20,
A2A7F7,
Q3UDB2,
Q497H7
UniParc:
UPI00005AC982,
UPI000059E219,
UPI00005904EA,
UPI000002308A
EMBL:
AL606929,
AF105990,
AF105996,
CH466594,
AF105993,
AF105992,
AF105988,
BC100550,
AF105997,
AK030192,
AK150159,
AF105995,
AF105998,
BC052466,
AF105991,
AF105994,
BC051017,
AF105989
Ensembl:
ENSMUSG00000029009
KO:
mmu:17769
|
| Nucleutide sequences |
EMBL-CDS:
EDL14796.1,
AAH52466.1,
AAD20313.1,
EDL14797.1,
EDL14794.1,
AAH51017.1,
BAC26832.1,
BAE29349.1,
AAI00551.1
Ensembl_TRS:
ENSMUST00000097788,
ENSMUST00000069604
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000095395,
ENSMUSP00000069774
RefSeq:
NP_034970.2,
NP_001155270.1
|
| Others |
UniRef100:
UniRef100_Q9WU20,
UniRef100_Q3UDB2
UniRef90:
UniRef90_Q9WU20
UniRef50:
UniRef50_P42898
UniGene:
Mm.89959
CCDS:
CCDS18929.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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