| Type | Description |
|---|---|
| Definition | Guanyl-specific ribonuclease pgl-1 |
| Date | Results | Publications |
|---|---|---|
| 2018-06-09 10:08:00 | study demonstrates that germ-granule components, PGL-1 and PGL-3, can serve as negative regulators of apoptosis not only in the germline but also in the soma in C. elegans. | 27650246 |
| 2017-07-15 10:19:00 | we show that removal of either of two critical P-granule components, PGL-1 or GLH-1, is sufficient to cause germ cells to express UNC-119::GFP and MYO-3 and to display RNA accumulation defects similar to those observed after depletion of P granules. Our data identify P granules as critical modulators of the germline transcriptome and guardians of germ cell fate. | 28258184 |
| 2016-12-17 11:26:00 | PGL-1 and PGL-3 control germline apoptosis in C. elegans. | 26598553 |
| 2014-02-22 10:09:00 | we demonstrated that mutations in C. elegans epg-11 cause the defective removal of PGL-1 and PGL-3 (cargo)-SEPA-1 (receptor) complexes, known as PGL granules, from somatic cells during embryogenesis | 24140420 |
| 2012-12-08 10:25:00 | findings show FBF-1 and FBF-2 have different effects on target mRNAs; FBF-2 prevents translation; FBF-2 activity depends on PGL-1; PGL-1 is required to localize FBF-2 to perinuclear P granules and for efficient binding of FBF-2 to its mRNA targets | 22991439 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
Q304E5_CAEEL
UniprotKB:
Q304E5
UniParc:
UPI000017BD07
EMBL:
BX284604
EnsemblGenome:
WBGene00003992
KO:
cel:CELE_ZK381.4
|
| Nucleutide sequences |
EMBL-CDS:
CCD62011.1
Gene_ORFName:
CELE_ZK381.4,
ZK381.4
|
| Protein sequencees |
RefSeq:
NP_001041066.1,
NP_001367362.1
|
| Others |
UniRef100:
UniRef100_Q9TZQ3
UniRef90:
UniRef90_Q9TZQ3
UniRef50:
UniRef50_G5EBV6
UniGene:
Cel.23408
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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