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176877 pig-1

176877

pig-1

Maternal embryonic leucine zipper kinase

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Maternal embryonic leucine zipper kinase

研究结论

Date Results Publications
2020-11-21 13:18:00 PIG-1 MELK-dependent phosphorylation of nonmuscle myosin II promotes apoptosis through CES-1 Snail partitioning. 32946434
2017-12-16 11:38:00 pig-1 MELK acts downstream of ces-1 Snail to cause the neurosecretory motor neuron neuroblast to divide asymmetrically by size and along the correct cell division axis. 28652378
2013-08-31 12:04:00 T169 residue in the PIG-1 activation loop is essential for PIG-1 activation by Par-4. 23267054
2012-09-15 10:30:00 PIG-1 promotes shed-cell detachment by preventing the cell-surface expression of cell-adhesion molecules; findings reveal a mechanism for apoptotic cell elimination that is fundamentally distinct from that of canonical programmed cell death 22801495
2010-01-21 00:00:00 Results demonstrate that pig-1 regulates asymmetric divisions of neuroblasts that divide to produce an apoptotic cell and either a neural precursor or a neuron. 16774992

名称对应

Type IDs
Gene
UniProtKB-ID: MELK_CAEEL
UniprotKB: U4PR86
UniParc: UPI0003B044D7, UPI0003B02883, UPI0000E8AE2B, UPI0003B0DBE6, UPI0003B01DCD, UPI0003B01C1E, UPI0003B0B394, UPI0000E8AE2C
EMBL: FO081096
EnsemblGenome: WBGene00021012
KO: cel:CELE_W03G1.6
Nucleutide sequences
EMBL-CDS: CDH93079.1, CCD69087.1, CDH93082.1, CDH93080.1, CDH93081.1, CDH93078.1, CCD69088.1, CDH93083.1
Gene_ORFName: W03G1.6
EnsemblGenome_TRS: W03G1.6h.1, W03G1.6c.1, W03G1.6f.1, W03G1.6b.1, W03G1.6e.1, W03G1.6g.1, W03G1.6d.1, W03G1.6a.1
Protein sequencees
EnsemblGenome_PRO: W03G1.6c.1, W03G1.6f.1, W03G1.6h.1, W03G1.6e.1, W03G1.6b.1, W03G1.6d.1, W03G1.6a.1, W03G1.6g.1
RefSeq: NP_001294357.1, NP_001294354.1, NP_001294353.1, NP_001368239.1, NP_001023420.2, NP_001368238.1, NP_001023421.2, NP_001294358.1
Others
UniRef100: UniRef100_U4PR86
UniRef90: UniRef90_U4PR86
UniRef50: UniRef50_U4PR86
UniGene: Cel.5632

全选

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研究热度

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