| Type | Description |
|---|---|
| Definition | 3'-5' exonuclease eri-1 |
| Date | Results | Publications |
|---|---|---|
| 2017-03-18 11:04:00 | In the absence of eri-1, reserpine mediated lifespan extension (RMLE) is shortened. In the dop-3 loss-of-function background, lack of eri-1 completely abolishes RMLE. This suggests that dop-3 and eri-1 act in independent parallel pathways for RMLE and these two pathways are essential and sufficient for the longevity enhancement by reserpine in C. elegans. | 27966489 |
| 2010-02-22 11:32:00 | results identify novel components of the endo machinery, demonstrate differential requirements for the Eri factors in the sperm-producing germline, and begin to delineate the functional requirement for the ERI/DICER complex in sperm development | 19797044 |
| 2010-01-21 00:00:00 | In C. elegans, two protein isoforms of ERI-1 are localized to the cytoplasm, and each has distinct functions in ribosomal RNA processing and negative regulation of RNA interference. | 18438419 |
| 2010-01-21 00:00:00 | After exposure to dsRNA or siRNAs, animals with eri-1 mutations accumulate more siRNAs than wild-type animals; a negative regulator that may normally function to limit the duration, cell-type specificity or endogenous functions of RNA interference | 14961122 |
| 2010-01-21 00:00:00 | These results provide additional support for the hypothesis that RRF-3 and ERI-1 act together in the endo-siRNA pathway, and furthermore suggests their involvement in additional biological processes. | 17919598 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
ERI1_CAEEL
UniprotKB:
O44406
UniParc:
UPI000007D425,
UPI00000786A0
EMBL:
FO081716
EnsemblGenome:
WBGene00001332
KO:
cel:CELE_T07A9.5
|
| Nucleutide sequences |
EMBL-CDS:
CCD73975.1,
CCD73976.1
Gene_ORFName:
T07A9.5
EnsemblGenome_TRS:
T07A9.5a.1,
T07A9.5b.1
|
| Protein sequencees |
EnsemblGenome_PRO:
T07A9.5a.1,
T07A9.5b.1
RefSeq:
NP_741292.1,
NP_741293.1,
NP_001368343.1,
NP_001368344.1
|
| Others |
UniRef100:
UniRef100_O44406
UniRef90:
UniRef90_O44406
UniRef50:
UniRef50_O44406
UniGene:
Cel.12380
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员