| Type | Description |
|---|---|
| Definition | Probable clathrin heavy chain 1 |
| Date | Results | Publications |
|---|---|---|
| 2014-08-23 10:53:00 | The clathrin heavy chain CHC-1 negatively regulates pulling forces acting on centrosomes during interphase and on spindle poles during mitosis in one-cell C. elegans embryos. | 24961801 |
| 2013-09-28 10:41:00 | Inactivating epn-1 or chc-1 disrupts engulfment by impairing actin polymerization. CHC-1 is enriched on extending pseudopods together with EPN-1, in an EPN-1-dependent manner. | 23861060 |
| 2010-01-21 00:00:00 | Loss of SNX-1, RME-8, or the clathrin chaperone Hsc70/HSP-1 leads to over-accumulation of endosomal clathrin, reduced clathrin dynamics, and missorting of MIG-14 to the lysosome. | 19763082 |
| 2010-01-21 00:00:00 | These results indicate that a high level of CHC activity is required for receptor-mediated endocytosis in nonneuronal cells but is largely dispensable for maintenance of synaptic vesicle pools. | 19151157 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CLH_CAEEL
UniprotKB:
P34574
UniParc:
UPI0000127AC1
EMBL:
Z30423
EnsemblGenome:
WBGene00011867
KO:
cel:CELE_T20G5.1
|
| Nucleutide sequences |
EMBL-CDS:
CAA83003.1
Gene_ORFName:
T20G5.1
EnsemblGenome_TRS:
T20G5.1.1
|
| Protein sequencees |
EnsemblGenome_PRO:
T20G5.1.1
RefSeq:
NP_499260.1
|
| Others |
UniRef100:
UniRef100_P34574
UniRef90:
UniRef90_P34574
UniRef50:
UniRef50_P29742
UniGene:
Cel.5115
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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