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176210 gpr-1

176210

gpr-1

G-protein regulator 1

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition G-protein regulator 1

研究结论

Date Results Publications
2017-06-10 11:47:00 Progeny of these animals (F2) inherit either only F0 maternal or only F0 paternal chromosomes, and thus descend from only either of their grandparents' gametes. 27479498
2017-05-06 13:17:00 Four distinct in vivo phosphorylated LIN-5 residues were found to have critical functions in spindle positioning. Two of these residues form part of a 30 amino acid binding site for GPR-1, which we identified by reverse two-hybrid screening. These LIN-5 phosphorylations promote LIN-5-GPR-1/2 interaction and contribute to cortical pulling forces 27711157
2013-03-23 10:31:00 GPR-1/2 can sense mechanical properties of the cortex, which may be important for GPR-1/2 function regulating spindle positioning and cytokinesis. 22927044
2011-08-27 12:17:00 Data demonstrate that GPB-1 depletion results in the loss of GPR-1/2 asymmetry during mitosis. 21652650
2010-01-21 00:00:00 Data suggest a mechanism in which RIC-8 favors generation of Galpha free from Gbetagamma and enables GPR-1/2 to mediate asymmetric cell division. 15479639

名称对应

Type IDs
Gene
UniProtKB-ID: GPR1_CAEEL
UniprotKB: Q95QJ7
UniParc: UPI000004E824
EMBL: FO080222
EnsemblGenome: WBGene00001688
KO: cel:CELE_F22B7.13
Nucleutide sequences
EMBL-CDS: CCD62140.1
Gene_ORFName: F22B7.13
EnsemblGenome_TRS: F22B7.13.1
Protein sequencees
EnsemblGenome_PRO: F22B7.13.1
RefSeq: NP_498900.1
Others
UniRef100: UniRef100_Q95QJ7
UniRef90: UniRef90_Q95QJ7
UniRef50: UniRef50_Q95QJ7
UniGene: Cel.8150

全选

研究热度
该基因近6年没有文献发表
热点单位
排名 科研单位 文献
1

Swiss Institute for Experimental Cancer Research (ISREC)

4
2

Utrecht University

3
3

Dana-Farber Cancer Institute

2
4

Max Planck Institute for Biophysical Chemistry

2
5

University of California

2
热点人员
排名 研究人员 文献
1

Pierre Gönczy

7
2

Mike Boxem

6
3

Sander van den Heuvel

5
4

David P Siderovski

5
5

Francis S Willard

5
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