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176138 dcr-1

176138

dcr-1

Death-promoting deoxyribonuclease

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Death-promoting deoxyribonuclease

研究结论

Date Results Publications
2016-07-28 17:31:00 role for pash-1 in miRNA maturation and miRNA-mediated gene regulation. 15531879
2015-03-28 13:15:00 Report of transcriptome-wide map of Dicer targets; identify thousands of Dicer-binding sites in human cells and C. elegans; find known and hundreds of additional miRNAs; also report structural RNAs, promoter RNAs, and mitochondrial transcripts as Dicer targets; most Dicer-binding sites reside on mRNAs/lncRNAs and are not significantly processed into small RNAs. 25416952
2014-09-27 10:10:00 Cleavage of DCR-1 by caspase 3 may cause a conformational change that allows truncated DCR-1 to bind and process DNA, and may remove steric hindrance that blocks DNA access to truncated DCR-1. 24323044
2014-08-16 10:14:00 [review] Dicer-1 lacks a functional helicase domain and is responsible for processing pre-microRNAs into mature miRNAs. 24556400
2013-11-30 11:02:00 Taken together, these results uncover a previously unknown role for DCR-1/Dicer in C. elegans antibacterial immunity that is largely associated with miRNA processing. 23918784

名称对应

Type IDs
Gene
UniProtKB-ID: DCR1_CAEEL
UniprotKB: P34529
UniParc: UPI0002530C6E
EMBL: FO081380
EnsemblGenome: WBGene00000939
KO: cel:CELE_K12H4.8
Nucleutide sequences
EMBL-CDS: CCD71200.2
Gene_ORFName: K12H4.8
EnsemblGenome_TRS: K12H4.8.2, K12H4.8.1
Protein sequencees
EnsemblGenome_PRO: K12H4.8.2, K12H4.8.1
RefSeq: NP_498761.2
Others
UniRef100: UniRef100_P34529
UniRef90: UniRef90_P34529
UniRef50: UniRef50_P34529
UniGene: Cel.38691

全选

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研究热度

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