| Type | Description |
|---|---|
| Definition | Partitioning defective protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2017-09-23 13:51:00 | PAR-3 exists in a dynamic equilibrium between an unclustered form and a clustered form, in response to cortical tension mainly exerted by actomyosin contractility. Cortical forces and CDC-42 control clustering of PAR proteins for Caenorhabditis elegans embryonic polarization. | 28737772 |
| 2017-05-13 20:32:00 | we find that vab-1 lies in the same genetic pathway as cdc-42 and is responsible for polarizing CDC-42 activity to the medial tip. Together, these data establish a previously uncharacterized role for polarized CDC-42, in conjunction with PAR-6, PAR-3 and an Eph receptor(vab-1), during epithelial intercalation. | 27861585 |
| 2013-03-23 11:53:00 | PAR-3 and PAR-6 function in cytokinesis may be partially redundant and play a role in the maintenance of DYN-1 in the cleavage furrow. | 22887994 |
| 2012-08-11 10:59:00 | Centrosomes localize apically by first moving toward lateral foci of the conserved polarity proteins PAR-3 and PAR-6, then move together with these foci toward the future apical surface. Embryos lacking PAR-3 fail to localize their centrosomes apically. | 22425160 |
| 2012-07-07 11:58:00 | a model of interactions between the Par proteins that includes both mutual inhibition and PAR-3 oligomerization | 21943422 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PAR3_CAEEL,
U4PRG6_CAEEL,
U4PM75_CAEEL,
U4PEM0_CAEEL,
U4PEL6_CAEEL,
U4PRH0_CAEEL
UniprotKB:
Q17353,
U4PRG6,
U4PM75,
U4PEM0,
U4PEL6,
U4PRH0
UniParc:
UPI0003B0F6F9,
UPI0003B0E62E,
UPI0003B046F6,
UPI0003B02781,
UPI000007F99F,
UPI000007B9C4,
UPI0003B0C3C3,
UPI00006CA2A9
EMBL:
FO080172,
U25032,
BX284603
EnsemblGenome:
WBGene00003918
KO:
cel:CELE_F54E7.3
|
| Nucleutide sequences |
EMBL-CDS:
CCD61764.1,
CCD61765.1,
CCD61766.1,
AAB18670.1,
CDH93170.1,
CDH93174.1,
CDH93176.1,
CDH93171.1,
CDH93175.1
Gene_ORFName:
F54E7.3,
F54E7.3,
CELE_F54E7.3,
F54E7.3,
CELE_F54E7.3,
F54E7.3,
CELE_F54E7.3,
CELE_F54E7.3,
F54E7.3,
CELE_F54E7.3,
F54E7.3
EnsemblGenome_TRS:
F54E7.3b.2,
F54E7.3a.1,
F54E7.3b.1,
F54E7.3c.1
|
| Protein sequencees |
EnsemblGenome_PRO:
F54E7.3c.1,
F54E7.3b.1,
F54E7.3a.1,
F54E7.3b.2
RefSeq:
NP_001293665.1,
NP_001368259.1,
NP_001022607.1,
NP_001293668.1,
NP_001370324.1,
NP_001293670.1,
NP_001360237.1,
NP_001360234.1,
NP_001367341.1,
NP_001368258.1,
NP_001293669.1,
NP_001368260.1,
NP_001293664.1
|
| Others |
UniRef100:
UniRef100_U4PEM0,
UniRef100_U4PEL6,
UniRef100_Q17353,
UniRef100_U4PRH0,
UniRef100_U4PM75,
UniRef100_U4PRG6
UniRef90:
UniRef90_Q17353,
UniRef90_U4PRH0
UniRef50:
UniRef50_Q17353
UniGene:
Cel.5328
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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