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175499 brc-1

175499

brc-1

Breast cancer type 1 susceptibility protein homolog

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Breast cancer type 1 susceptibility protein homolog

研究结论

Date Results Publications
2020-09-12 16:03:00 BRCA1-associated structural variations are a consequence of polymerase theta-mediated end-joining. 32680986
2019-07-20 11:13:00 the C. elegans homologs of the BRCA1/BARD1 tumor suppressor genes, brc-1/brd-1, were identified as mediators of the anti-apoptotic effect but dispensable for lifespan extension upon mitochondrial stress. 30366941
2015-02-07 13:02:00 Data suggest that BRC-1/BRD-1 can both promote and antagonize genome stability depending on whether homologous recombination is initiated during DNA double-strand break repair or during replication stalling. 24424777
2010-05-31 11:37:00 BRAP-2 is necessary for preventing an inappropriate response to elevated levels of reactive oxygen species by countering premature activation of BRC-1 and CKI-1. 20207739
2010-01-21 00:00:00 Ce-BRC-1 and Ce-BRD-1 share a role in C. elegans DNA repair processes. 14711411

名称对应

Type IDs
Gene
UniProtKB-ID: BRCA1_CAEEL
UniprotKB: B6VQ60
UniParc: UPI0001838775, UPI0001838776
EMBL: BX284603
EnsemblGenome: WBGene00000264
Nucleutide sequences
EMBL-CDS: CAR97813.1, CAR97812.1
Gene_ORFName: C36A4.8
EnsemblGenome_TRS: C36A4.8a.1, C36A4.8b.1
Protein sequencees
EnsemblGenome_PRO: C36A4.8a.1, C36A4.8b.1
RefSeq: NP_001366800.1, NP_001254882.1, NP_001367205.1
Others
UniRef100: UniRef100_B6VQ60
UniRef90: UniRef90_B6VQ60
UniRef50: UniRef50_B6VQ60
UniGene: Cel.17518

全选

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研究热度

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