| Type | Description |
|---|---|
| Definition | 5'-3' exoribonuclease 2 homolog |
| Date | Results | Publications |
|---|---|---|
| 2017-05-27 11:32:00 | De-repression appears to be triggered such that more robust XRN2 perturbation, by elimination of both PAXT-1 and BPNT1, is less detrimental to worm viability than absence of PAXT-1 alone. Indeed, we find that two distinct XRN2 repression mechanisms are alleviated at different thresholds of XRN2 inactivation. Like more than 15% of C. elegans genes, xrn-2 occurs in an operon, and we identify additional | 27631780 |
| 2016-07-02 11:58:00 | In Caenorhabditis elegans, XRN-2 functions with PAXT-1, which shares a putative XRN-2-binding domain (XTBD) with otherwise unrelated mammalian proteins. The study characterizes the structure and function of an XTBD-XRN2 complex. | 26779609 |
| 2014-06-28 10:31:00 | XRN2 has unanticipated miRNA specificity in vivo, and its diverse developmental functions may relate to distinct substrates. | 24445807 |
| 2010-01-21 00:00:00 | degradation of mature miRNAs in the nematode Caenorhabditis elegans, mediated by the 5'-->3' exoribonuclease XRN-2, affects functional miRNA homeostasis in vivo | 19734881 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
XRN2_CAEEL
UniprotKB:
Q9U299
UniParc:
UPI00017570AB
EMBL:
AL110490
EnsemblGenome:
WBGene00006964
KO:
cel:CELE_Y48B6A.3
|
| Nucleutide sequences |
EMBL-CDS:
CAB54449.2
Gene_ORFName:
Y48B6A.3
EnsemblGenome_TRS:
Y48B6A.3.1
|
| Protein sequencees |
EnsemblGenome_PRO:
Y48B6A.3.1
RefSeq:
NP_496958.2
|
| Others |
UniRef100:
UniRef100_Q9U299
UniRef90:
UniRef90_Q9U299
UniRef50:
UniRef50_Q9U299
UniGene:
Cel.14046
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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