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174643 nphp-1

174643

nphp-1

Nephrocystin-1-like protein

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Nephrocystin-1-like protein

研究结论

Date Results Publications
2016-07-28 13:16:00 NPHP-1 and NPHP-4 proteins play important and redundant roles in facilitating ciliary sensory signal transduction. 15817158
2012-07-09 02:09:00 We propose that NPHP-1 and NPHP-4 act globally at the TZ to regulate ciliary access of the IFT machinery, axonemal structural components, and signaling molecules, and that perturbing this balance results in cell type-specific phenotypes. 18316409
2010-01-21 00:00:00 The NPHP homologs may be necessary for initial assembly of the cilium, whereas the polycystic kidney disease homologs may function as sensory transducers. 15659564
2010-01-21 00:00:00 The C. elegans B9 proteins form a complex that localizes to the base of cilia. Mutations in the B9 genes do not overtly affect cilia formation unless they are in combination with a mutation in nph-1 or nph-4. 18337471

名称对应

Type IDs
Gene
UniProtKB-ID: NPHP1_CAEEL
UniprotKB: O17972
UniParc: UPI00001303E2
EMBL: Z49911
EnsemblGenome: WBGene00010898
KO: cel:CELE_M28.7
Nucleutide sequences
EMBL-CDS: CAA90133.1
Gene_ORFName: M28.7
EnsemblGenome_TRS: M28.7.1
Protein sequencees
EnsemblGenome_PRO: M28.7.1
RefSeq: NP_496298.1
Others
UniRef100: UniRef100_O17972
UniRef90: UniRef90_O17972
UniRef50: UniRef50_O17972
UniGene: Cel.14718

全选

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