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174267 lin-5

174267

lin-5

Spindle apparatus protein lin-5

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Spindle apparatus protein lin-5

研究结论

Date Results Publications
2020-06-06 12:02:00 mitotic kinase PLK-1 affects cell polarity via the enrichment in somatic AB cells, which limits the cortical localization of the dynein-binding NuMA orthologue LIN-5 31645459
2017-05-20 14:17:00 LIN-5 is required for EMS spindle positioning, possibly through a Galpha- and DLG-1-independent mechanism. 27672093
2017-05-06 13:17:00 Four distinct in vivo phosphorylated LIN-5 residues were found to have critical functions in spindle positioning. Two of these residues form part of a 30 amino acid binding site for GPR-1, which we identified by reverse two-hybrid screening. These LIN-5 phosphorylations promote LIN-5-GPR-1/2 interaction and contribute to cortical pulling forces 27711157
2011-12-10 10:51:00 Data show that Phospho-LIN-5 co-localizes with at the anterior cell cortex and temporally coincides with a switch from anterior- to posterior-directed spindle movements in the one-cell embryo. 21857670
2010-01-21 00:00:00 ASPM-1, together with calmodulin (CMD-1), promotes meiotic spindle organization and the accumulation of LIN-5 at meiotic and mitotic spindle poles. 19219036

名称对应

Type IDs
Gene
UniProtKB-ID: LIN5_CAEEL
UniprotKB: P45970
UniParc: UPI000012E6A0
EMBL: AF240692, Z36753
EnsemblGenome: WBGene00002994
KO: cel:CELE_T09A5.10
Nucleutide sequences
EMBL-CDS: CAA85342.1, AAF61239.1
Gene_ORFName: T09A5.10
EnsemblGenome_TRS: T09A5.10.2, T09A5.10.1
Protein sequencees
EnsemblGenome_PRO: T09A5.10.1, T09A5.10.2
RefSeq: NP_495654.1
Others
UniRef100: UniRef100_P45970
UniRef90: UniRef90_P45970
UniRef50: UniRef50_P45970
UniGene: Cel.18238

全选

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研究热度

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