| Type | Description |
|---|---|
| Definition | Defective in germ line development protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2015-10-31 11:04:00 | picture that emerges from the structural and biochemical data are that GLD-3 activates GLD-2 both indirectly by stabilizing the enzyme and directly by contributing positively charged residues near the RNA-binding cleft | 26124149 |
| 2013-04-06 12:21:00 | Data indicate that a 10-amino-acid region in germline development defective-3 (GLD-3) is required for fem-3 binding factor (FBF) binding, while a 7-amino-acid loop in FBF between PUF repeats 7 and 8 is necessary for GLD-3 binding. | 23159559 |
| 2010-11-27 10:09:00 | report the 2.8-A-resolution crystal structure of a proteolytically stable fragment encompassing the KH2, KH3, KH4, and KH5 domains of C. elegans GLD-3 | 20823118 |
| 2010-01-21 00:00:00 | In C. elegans hermaphrodites, gamete production begins with spermatogenesis and transitions later to oogenesis; the combinatorial use of GLD-2 contributes to this transition, as GLD-2/GLD-3 promotes spermatogenesis, and GLD-2/RNP-8 specifies oogenesis. | 19460348 |
| 2010-01-21 00:00:00 | In germ cells, GLD-3 promotes the transition from mitosis to meiosis primarily via its interaction with GLD-2, and it promotes spermatogenesis primarily via its interaction with FBF. | 15454534 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GLD3_CAEEL
UniprotKB:
Q95ZK7
UniParc:
UPI0001721C04,
UPI0002656E3C
EMBL:
BX284602
EnsemblGenome:
WBGene00001597
KO:
cel:CELE_T07F8.3
|
| Nucleutide sequences |
EMBL-CDS:
CCD65918.1,
CCD65916.1
Gene_ORFName:
T07F8.3
EnsemblGenome_TRS:
T07F8.3a.1,
T07F8.3b.1
|
| Protein sequencees |
EnsemblGenome_PRO:
T07F8.3b.1,
T07F8.3a.1
RefSeq:
NP_495480.1,
NP_495479.2
|
| Others |
UniRef100:
UniRef100_Q95ZK7
UniRef90:
UniRef90_Q95ZK7
UniRef50:
UniRef50_Q95ZK7
UniGene:
Cel.34183
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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