| Type | Description |
|---|---|
| Definition | myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 |
| Date | Results | Publications |
|---|---|---|
| 2019-06-29 12:51:00 | Together these data are the first to demonstrate that Af10-dependent H3K79me is essential for development of nasal processes and adjacent tissues, and consequent midfacial formation. | 28931923 |
| 2018-12-22 11:01:00 | In lung metastasis sites, the knockdown of MLLT10 in SW620 cells significantly inhibited Vimentin expression, whereas the E-Cadherin was increased. These results indicate that MLLT10 regulates the metastasis of CRC cells via EMT. | 30102091 |
| 2015-02-14 13:18:00 | Results provide evidence that transformation driven by MLL fusions as well as the recurrent AML-associated NUP98-NSD1 fusion oncogene is critically dependent on the ability of AF10 to stimulate DOT1L activity. | 25464900 |
| 2014-05-10 11:04:00 | During leukemogenesis, CALM-AF10 plays critical roles in the cytoplasm. | 24397609 |
| 2012-03-24 11:14:00 | In leukemia cells, full-length CALM-AF10 localized to the nucleus with no consistent effect on growth factor endocyctosis, and suppressed histone H3 lysine 79 methylation regardless of the presence of clathrin | 21706055 |
| Type | IDs |
|---|---|
| Synonymous | Af10, B130021D15Rik, D630001B22Rik, mKIAA4140 |
| Gene |
UniProtKB-ID:
AF10_MOUSE,
A2AS70_MOUSE
UniprotKB:
O54826,
A2AS70
UniParc:
UPI00001EEA3A,
UPI000024DD73
EMBL:
AL928557,
CH466542,
BC070475,
AL928589,
AF010135
Ensembl:
ENSMUSG00000026743
KO:
mmu:17354
|
| Nucleutide sequences |
EMBL-CDS:
AAD11570.1,
EDL08096.1,
AAH70475.1,
EDL08097.1
Ensembl_TRS:
ENSMUST00000028076,
ENSMUST00000114680,
ENSMUST00000114671
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028076,
ENSMUSP00000110328,
ENSMUSP00000110319
RefSeq:
XP_030104047.1,
XP_006497445.2,
XP_036014924.1,
XP_036014941.1,
XP_030104016.1,
XP_036014920.1,
XP_036014942.1,
XP_036014931.1,
XP_017171562.1,
XP_036014927.1,
NP_034934.2,
XP_030103987.1,
XP_030104053.1,
XP_036014929.1,
XP_030103980.1,
XP_036014937.1,
XP_006497436.2,
XP_030104038.1,
XP_030104014.1,
XP_036014930.1,
XP_030103972.1,
NP_001239489.1,
XP_030104060.1,
XP_036014935.1,
XP_030104056.1,
XP_006497453.1,
XP_036014925.1,
XP_036014933.1,
XP_006497438.2,
XP_036014928.1,
XP_036014912.1,
XP_036014934.1,
XP_017171569.1,
XP_030103976.1,
XP_030103974.1,
XP_030103999.1,
XP_036014932.1,
XP_006497452.1,
XP_030104054.1,
XP_036014926.1,
NP_001239490.1,
XP_030103973.1,
XP_030104055.1,
XP_006497440.2,
XP_030104070.1,
XP_030103996.1,
XP_030104028.1,
XP_030104057.1
|
| Others |
UniRef100:
UniRef100_O54826,
UniRef100_A2AS70
UniRef90:
UniRef90_O54826
UniRef50:
UniRef50_P55197
UniGene:
Mm.209175
CCDS:
CCDS15708.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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