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17305 Mfng

17305

Mfng

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

protein-coding

Mus musculus

基因描述

Type Description
Definition MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

研究结论

Date Results Publications
2018-12-22 11:36:00 MFNG imposes a negative correlation between Jag1 and Notch, being high Jag1 in the absence of MFNG predictive of poor prognosis. 30065304
2017-11-11 12:31:00 These results show that Notch signaling is finely calibrated in the cochlea via Lfng and Mfng to produce precisely tuned levels of signaling that first set the boundary of the organ of Corti and later regulate hair cell development. 27966429
2017-06-24 10:27:00 Fringe modifications at EGF8 and EGF12 enhanced Notch1 binding to and activation from Delta-like 1, while modifications at EGF6 and EGF36 (added by Manic and Lunatic but not Radical) inhibited Notch1 activation from Jagged1. 28089369
2016-05-21 13:03:00 each Fringe contributes to T and B cell development, and Fringe is required for optimal in vitro stimulation of T and B cells. 26608918
2012-05-12 10:04:00 the presence of Gal on O-fucose glycans differentially affects DLL1-induced NOTCH signaling modulated by LFNG versus MFNG 22081605

名称对应

Type IDs
Synonymous AW546563
Gene
UniProtKB-ID: MFNG_MOUSE, Q3UPI0_MOUSE
UniprotKB: O09008, Q3UPI0
UniParc: UPI000002158E
EMBL: AF015769, AK143523, BC010983, U94349
Ensembl: ENSMUSG00000018169
KO: mmu:17305
Nucleutide sequences
EMBL-CDS: AAC53260.1, AAH10983.1, AAB71669.1, BAE25415.1
Ensembl_TRS: ENSMUST00000018313
Protein sequencees
Ensembl_PRO: ENSMUSP00000018313
RefSeq: XP_006520614.1, XP_017171981.1, XP_006520615.1, XP_036015108.1, NP_032621.1
Others
UniRef100: UniRef100_O09008
UniRef90: UniRef90_O09008
UniRef50: UniRef50_O09008
UniGene: Mm.149235
CCDS: CCDS27622.1

全选

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研究热度

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