| Type | Description |
|---|---|
| Definition | Leucine-rich repeat serine/threonine-protein kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-07-07 11:29:00 | LRRK2 functions together with a second Parkinson's disease-associated gene, RAB7L1, within an evolutionarily conserved genetic module in diverse cellular contexts. | 27424887 |
| 2016-12-17 10:24:00 | Study investigated the role of UNC-23 and HSP-1 on LRK-1 function in C. elegans; results suggest that the UNC-23-HSP-1 chaperone complex regulates LRK-1 localization to the Golgi apparatus and consequently determines the polarized sorting of synaptic vesicle proteins to the axons. | 26853528 |
| 2015-11-21 10:51:00 | Lack of Grx1 homolog exacerbates LRRK2-mediated dopaminergic neurodegeneration in Caenorhabditis elegans. | 25355420 |
| 2012-02-18 10:35:00 | Findings establish a critical functional link between LRRK2 and ER stress. | 21857923 |
| 2010-01-21 00:00:00 | Study identified a novel protein kinase LRK-1, a C. elegans homolog of the familial Parkinsonism gene PARK8/LRRK2 that is required for polarized localization of synaptic vesicle proteins. | 17346966 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
LRK1_CAEEL
UniprotKB:
Q9TZM3
UniParc:
UPI0000F53535
EMBL:
AB297384,
FO081425
EnsemblGenome:
WBGene00003068
KO:
cel:CELE_T27C10.6
|
| Nucleutide sequences |
EMBL-CDS:
BAF48647.1,
CCD71547.1
Gene_ORFName:
T27C10.6
EnsemblGenome_TRS:
T27C10.6.1
|
| Protein sequencees |
EnsemblGenome_PRO:
T27C10.6.1
RefSeq:
NP_492839.4
|
| Others |
UniRef100:
UniRef100_Q9TZM3
UniRef90:
UniRef90_Q9TZM3
UniRef50:
UniRef50_Q9TZM3
UniGene:
Cel.20322
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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