| Type | Description |
|---|---|
| Definition | Protein maternal effect lethal 26 |
| Date | Results | Publications |
|---|---|---|
| 2018-11-24 11:21:00 | KLHL22 plays a conserved role to mediate the activation of mTORC1 and downstream events in mammals and nematodes; depletion of MEL-26, the Caenorhabditis elegans orthologue of KLHL22, extends worm lifespan | 29769719 |
| 2012-12-22 10:44:00 | study demonstrates that the level of MEI-1 protein is reduced in an unc-89 mutant, indicating that the normal role of UNC-89 is to inhibit the CUL-3/MEL-26 complex toward MEI-1 in striated muscle | 22621901 |
| 2010-01-21 00:00:00 | The BTB-containing protein MEL-26 is a component required for degradation of MEI-1 in vivo; importantly, MEL-26 specifically interacts with CUL-3 and MEI-1 in vivo and in vitro, and displays properties of a substrate-specific adaptor | 13679921 |
| 2010-01-21 00:00:00 | KO8F11.3 regulates mel-26 in the helminth embryo. | 17403899 |
| 2010-01-21 00:00:00 | MEL-26 not only acts as a substrate-specific adaptor within the MEL-26/CUL-3 complex, but also promotes cytokinesis by a CUL-3- and microtubule-independent mechanism. | 16169482 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
MEL26_CAEEL,
K8F7T2_CAEEL
UniprotKB:
Q94420,
K8F7T2
UniParc:
UPI0002997B8A,
UPI000007E336
EMBL:
BX284601,
U67737,
Z79759
EnsemblGenome:
WBGene00003209
KO:
cel:CELE_ZK858.4
|
| Nucleutide sequences |
EMBL-CDS:
AAC63596.1,
CAB02139.2,
CCO25606.1
Gene_ORFName:
ZK858.4,
CELE_ZK858.4,
ZK858.4
EnsemblGenome_TRS:
ZK858.4a.1
|
| Protein sequencees |
EnsemblGenome_PRO:
ZK858.4a.1
RefSeq:
NP_492449.2,
NP_001263463.1
|
| Others |
UniRef100:
UniRef100_K8F7T2,
UniRef100_Q94420
UniRef90:
UniRef90_K8F7T2,
UniRef90_Q94420
UniRef50:
UniRef50_Q94420
UniGene:
Cel.5086
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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