| Type | Description |
|---|---|
| Definition | Retinoblastoma-like protein homolog lin-35 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-16 10:45:00 | Study reports that LIN-35 indeed mediates the association of E2F-DP and MuvB, a function that stabilizes (Dp/Retinoblastoma(Rb)-like/E2F/MuvB) or DREAM transcriptional repressor complex subunit occupancy at target genes. In the absence of LIN-35, the occupancy of E2F-DP and MuvB at most DREAM target genes decreases dramatically and many of those genes become upregulated. | 29091720 |
| 2015-12-12 10:14:00 | Simultaneous mutation of lin-35 and fzr-1, an orthologue to Cdh1, completely eliminates the essential requirement of CDK4/6-cyclin D (CDK-4/CYD-1) in C. elegans. | 25562820 |
| 2014-08-09 11:02:00 | CED-9/Bcl-2 downregulation via LIN-35/Rb triggers germ cell apoptosis in C. elegans in response to starvation. | 24752899 |
| 2014-01-18 12:25:00 | Tumor suppressor Rb maintains the "starvation-induced" transcriptome and represses the "refeeding-induced" transcriptome, including the repression of many pathogen-, toxin-, and oxidative-stress-inducible and metabolic genes. | 23664972 |
| 2012-09-08 11:18:00 | The function of LIN-35/Rb is to prevent germline gene expression in the soma | 22412383 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
LIN35_CAEEL
UniprotKB:
G5EDT1
UniParc:
UPI0000060E54
EMBL:
BX284601,
AF116529
EnsemblGenome:
WBGene00003020
KO:
cel:CELE_C32F10.2
|
| Nucleutide sequences |
EMBL-CDS:
CCD61908.1,
AAD05570.1
Gene_ORFName:
C32F10.2
EnsemblGenome_TRS:
C32F10.2.1
|
| Protein sequencees |
EnsemblGenome_PRO:
C32F10.2.1
RefSeq:
NP_491686.1
|
| Others |
UniRef100:
UniRef100_G5EDT1
UniRef90:
UniRef90_G5EDT1
UniRef50:
UniRef50_G5EDT1
UniGene:
Cel.5952
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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