| Type | Description |
|---|---|
| Definition | MAP kinase-activated protein kinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 10:25:00 | IL-33-activated murine mast cells control the dichotomy between RORgammat(+) and Helios(+) Tregs via the MK2/3-mediated IL-6 production in vitro | 31334837 |
| 2020-05-23 12:43:00 | The MK2/3 are the only LPS-induced kinases for S52 and S178 of TTP and the role of MK2 and MK3 in the regulation of TNF biosynthesis is not restricted to phosphorylation of TTP at S52/S178 but includes independent processes, which could involve other TTP phosphorylations. | 31527197 |
| 2020-04-18 13:02:00 | MK2 is a serine/threonine kinase that functions downstream of p38 stress-activated mitogen-activated protein kinase with a role in experimental colitis | 31617572 |
| 2019-10-05 11:24:00 | This is the first study to demonstrate the critical role of the MK2 pathway in chemokine production, macrophage influx, macrophage function, and tumor growth. | 30298062 |
| 2019-10-05 10:05:00 | MK2 augments hepatic I/R injury and induces production. | 30483268 |
| Type | IDs |
|---|---|
| Synonymous | AA960234, MAPKAP-K2, MK-2, MK2, Rps6kc1 |
| Gene |
UniProtKB-ID:
MAPK2_MOUSE,
Q3U2P8_MOUSE
UniprotKB:
P49138,
Q3U2P8
UniParc:
UPI00001C23C9
EMBL:
X76850,
BC063064,
AK155171
Ensembl:
ENSMUSG00000016528
KO:
mmu:17164
|
| Nucleutide sequences |
EMBL-CDS:
CAA54183.1,
AAH63064.1,
BAE33092.1
Ensembl_TRS:
ENSMUST00000016672
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000016672
RefSeq:
NP_032577.1
|
| Others |
UniRef100:
UniRef100_P49138
UniRef90:
UniRef90_P49138
UniRef50:
UniRef50_P49138
UniGene:
Mm.221235,
Mm.490983
CCDS:
CCDS15266.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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