Syf2 - SYF2 pre-mRNA-splicing factor-BMKCloudï½ç¾è¿å®¢äº

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170933 Syf2

基因描述

Type	Description
Definition	SYF2 pre-mRNA-splicing factor

研究结论

Date	Results	Publications
2016-03-19 11:42:00	SYF2 protein expression was dramatically upregulated after retinal damage.	25944718
2015-05-30 12:36:00	the upregulation of SYF2 was associated with Schwann cell differentiation and migration following sciatic nerve crush.	24962097
2014-09-13 12:17:00	This study shows that SYF2 was significantly increased in the rat cerebral cortex after LPS injection, suggesting that SYF2 might be involved in the pathological processes of astrocyte proliferation and neuronal apoptosis.	24301298

名称对应

Type	IDs
Synonymous	Gcipip, P29
Gene	UniProtKB-ID: SYF2_RAT UniprotKB: Q4QRB2 UniParc: UPI0000029A9D EMBL: AF366369, BC097289 Ensembl: ENSRNOG00000060597 KO: rno:170933
Nucleutide sequences	EMBL-CDS: AAK53393.1, AAH97289.1 Ensembl_TRS: ENSRNOT00000091494
Protein sequencees	Ensembl_PRO: ENSRNOP00000072888 RefSeq: NP_596908.2
Others	UniRef100: UniRef100_Q9D198 UniRef90: UniRef90_Q9D198 UniRef50: UniRef50_O95926 UniGene: Rn.162117

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
28076346	Cryo-EM structure of a human spliceosome activated for step 2 of splicing. Nature Karl Bertram , Dmitry E Agafonov , Wen-Ti Liu , Olexandr Dybkov , Cindy L Will , Klaus Hartmuth , Henning Urlaub , Berthold Kastner , Holger Stark , Reinhard LuÌhrmann	2017-02-16	-
25944718	Upregulation of SYF2 Relates to Retinal Ganglion Cell Apoptosis and Retinal Glia Cell Proliferation After Light-Induced Retinal Damage. J. Mol. Neurosci. Aimin Sang , Xiaowei Yang , Hui Chen , Bai Qin , Manhui Zhu , Ming Dai , Rongrong Zhu , Xiaojuan Liu	2015-06-01	-
24962097	Involvement of upregulated SYF2 in Schwann cell differentiation and migration after sciatic nerve crush. Cell. Mol. Neurobiol. Zhengming Zhou , Yang Liu , Xiaoke Nie , Jianhua Cao , Xiaojian Zhu , Li Yao , Weidong Zhang , Jiang Yu , Gang Wu , Yonghua Liu , Huiguang Yang	2014-10-01	-
24301298	Upregulation of SYF2 is associated with neuronal apoptosis caused by reactive astrogliosis to neuroinflammation. J. Neurosci. Res. Wei Xu , Maohong Cao , Heyi Zheng , Xiang Tan , Lei Li , Gang Cui , Jian Xu , Jianhua Cao , Kaifu Ke , Qiyun Wu	2014-03-01	Syf2
23742842	Splicing and beyond: the many faces of the Prp19 complex. Biochim. Biophys. Acta Sittinan Chanarat , Katja StrÃ¤Ãer	2013-10-01	Crnkl1, Syf2, Hspa8, Xab2, Prpf19, Bcas2, Ctnnbl1, Ppie, Cwc15, Rbm22, Ppil1, Isy1, Ccdc12, Aqr, Snw1, Plrg1, Cdc5l, Bud31
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell Alfredo Castello , Bernd Fischer , Katrin Eichelbaum , Rastislav Horos , Benedikt M Beckmann , Claudia Strein , Norman E Davey , David T Humphreys , Thomas Preiss , Lars M Steinmetz , Jeroen Krijgsveld , Matthias W Hentze	2012-06-08	GNPDA1, SCARNA27, GABPB1-AS1, NFYC-AS1, FKSG29, PHKA2-AS1, HDAC6, PDCD6, C17orf96, LOC100287042, MIR3652, ARPC4-TTLL3, ATP5J2-PTCD1, TGIF2-C20orf24, FARSB, ABCC5, ABCF2, HUWE1, ARPC4, ARPC1B, ACTR3, ACTR1A, LRPPRC, TRAP1, BCAP31, NAMPT, RBM12, TOB1, G3BP1, SUGP2, MBNL2, ABI2, CEBPZ, ATP6AP2, SLC25A15, RCL1, RBM7, RBM6, RBM5, ALYREF, PSME3, MPHOSPH10, NUTF2, USPL1, DDX39A, STX6, HNRNPR, MRPS31, RIDA, SF3B4, AKAP8, STUB1, SIGMAR1, SMNDC1, BCAS2, SF3A1, CDKN2A, APBB3, SMYD5, ADAR, EMC8, NPM3, HMG20A, NOD1, RACK1, NDC80, NSA2, YAP1, CD2BP2, TUBGCP3, RBM14, EMG1, ACAA2, PPIE, TAB1, MAD2L2, PIBF1, SLC25A17, NXF1, CREB3, LRRC41, SYNCRIP, ENOX2, MYBBP1A, DDX17, ADARB2, CHERP, HYOU1, IPO8, NOP56, RNASEH2A, GLRX3, DCTN2, LAMTOR5, PRDX4, AGPAT1, RPP30, SLU7, MRPL28
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Mol. Cell Alexander G Baltz , Mathias Munschauer , BjÃ¶rn SchwanhÃ¤usser , Alexandra Vasile , Yasuhiro Murakawa , Markus Schueler , Noah Youngs , Duncan Penfold-Brown , Kevin Drew , Miha Milek , Emanuel Wyler , Richard Bonneau , Matthias Selbach , Christoph Dieterich , Markus Landthaler	2012-06-08	NBPF10, TSFM, LRPPRC, RBM12, G3BP1, SUGP2, MBNL2, CEBPZ, TRIM28, RBM7, RBM6, RBM5, ALYREF, MPHOSPH10, EIF1, DDX39A, HNRNPR, MRPS31, POP7, SRRM1, SF3B4, AKAP8, LOC400927-CSNK1E, SAP18, EIF1B, SF3A1, CDKN2A, ADAR, NPM3, RACK1, NSA2, ADARB1, RBM14, EMG1, NXF1, SYNCRIP, MYBBP1A, DDX17, CHERP, NOP56, PRPF8, IGF2BP1, IGF2BP3, IGF2BP2, KHDRBS3, KHDRBS1, CELF1, CELF2, KIF1C, SRSF10, UTP14A, CPSF4, TCERG1, RNPS1, SUB1, SRSF8, SF3A3, HNRNPA0, EBNA1BP2, CKAP4, ASCC3, GCN1, SF3B2, NUDT21, CPSF6, DDX52, CHD2, DUSP14, DIDO1, NUPL2, HNRNPUL1, KRR1, LSM6, PSIP1, STRAP, SUPT16H, MRPL3, ATXN2L, LARP4, DDX42, PDAP1, U2AF2, WBSCR22, KCTD12, CIRBP, MRPL54, FTSJ3, EXOSC6, CHCHD1, CLK3, CLTC, HIST4H4, ZC3H18, MSI2, MRPL10, RAVER1, C1orf131, RBM45, CPEB2
22448250	Disruption of murine mp29/Syf2/Ntc31 gene results in embryonic lethality with aberrant checkpoint response. PLoS ONE Chia-Hsin Chen , Po-Chen Chu , Liekyeow Lee , Huang-Wei Lien , Tse-Ling Lin , Chi-Chen Fan , Peter Chi , Chang-Jen Huang , Mau-Sun Chang	2012-01-01	Chek1, Chek2, Syf2, elavl3, syf2
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team	2004-10-01	Ldlrap1, Dnajc3, Rnaset2a, Btnl1, Isg15, Cyp3a41b, Ly6c2, Ccl21b, Eif3j2, Mup18, Lrrc19, Rcc1, 1700047I17Rik2, Pcsk9, Adat3, Tdrd7, Sco2, Gpr153, Pafah2, Gm44504, H6pd, Adprhl2, Gpn2, Rusc2, Stx12, Ppp1r8, Smpdl3b, Fam46b, Bsdc1, Slc44a1, Zfand2a, Rubcn, Kifc1, Pifo, C030017K20Rik, Cbarp, Rpl5, Micalcl, Atg14, Lrrc8c, Noc4l, Nsun5, Psph, Trrap, Mapre3, Ube3c, Tbc1d14, Hscb, Tyw1, Emilin1, Rab28, Pot1a, Parp11, Tada3, Tra2a, Brk1, Fbxl14, Phrf1, Plekha1, Gm21975, Ric8a, Mob2, Prkd2, Ccp110, Vrk3, Grwd1, Nlrp6, Trim68, Psip1, Spred3, Faap24, Ints4, Rrp8, Unc45a, Igflr1, Sf3b3, D8Ertd738e, Usb1, Champ1, Smim19, Exoc8, Gadd45gip1, Phkb, Dohh, Fam192a, Enkd1, Taf5l, Zdhhc7, Snapc2, Ak6, Gpat4, Dcun1d2, Ankrd10, Cog4, Hinfp, Lars2, Xylb, Imp3, Cmtm7

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