| Type | Description |
|---|---|
| Definition | low density lipoprotein receptor-related protein 6 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:15:00 | Cardiac-specific LRP6 knockout induces lipid accumulation through Drp1/CPT1b pathway in adult mice. | 31811407 |
| 2020-05-16 10:35:00 | Lrp5 and -6 are required for the self-renewal. | 30668923 |
| 2020-04-18 10:04:00 | the results of this study demonstrate that the inhibition of miR21 expression can alleviate nonalcoholic fatty liver disease by targeting LRP6 to activate the WNT/bcatenin signaling pathway. | 31638173 |
| 2020-03-21 11:55:00 | LRP6 is required to maintain the integrity of intercalated disc (ID) structure and the balance of ID proteins. | 31609038 |
| 2019-12-07 11:01:00 | MEG3 functions as a potential hepatocyte lipid degeneration suppressor. MEG3 helps to alleviate lipid over-deposition, probably by binding to miR-21 to regulate the expression of LRP6. | 30711569 |
| Type | IDs |
|---|---|
| Synonymous |
C030016K15Rik,
Cd,
Gw,
ska26,
ska |
| Gene |
UniProtKB-ID:
LRP6_MOUSE,
A0A0R4J0A9_MOUSE
UniprotKB:
O88572,
A0A0R4J0A9
UniParc:
UPI00002131A6,
UPI0000029920
EMBL:
BC060704,
AC163198,
AF074265,
AC155838
Ensembl:
ENSMUSG00000030201
KO:
mmu:16974
|
| Nucleutide sequences |
EMBL-CDS:
AAH60704.1,
AAC33007.1
Ensembl_TRS:
ENSMUST00000032322
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000032322
RefSeq:
XP_006505720.1,
NP_032540.2
|
| Others |
UniRef100:
UniRef100_A0A0R4J0A9,
UniRef100_O88572
UniRef90:
UniRef90_O75581
UniRef50:
UniRef50_O75581
UniGene:
Mm.321990
CCDS:
CCDS39678.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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