| Type | Description |
|---|---|
| Definition | Rho guanine nucleotide exchange factor (GEF) 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-12 11:22:00 | Arhgef1 plays a critical role in platelet function, in vitro and in vivo. | 30994039 |
| 2019-03-02 12:05:00 | data highlight the importance of Arhgef1 in cardiovascular disease and suggest targeting Arhgef1 as a potential therapeutic strategy against atherosclerosis. | 29130930 |
| 2017-11-18 13:23:00 | Arhgef1 controls the process of neurite formation in newborn cortical neurons derived from neural progenitor cells | 27923664 |
| 2017-05-06 10:28:00 | these findings reveal that Arhgef1 functions as a negative regulator of neurite outgrowth through regulating RhoA-cofilin pathway and actin dynamics. | 27489999 |
| 2012-08-25 10:20:00 | Upon beta(2)AR activation, both betaArrestin2 and p115RhoGEF translocate to the plasma membrane, with concomitant activation of RhoA and formation of focal adhesions and stress fibers. | 22500016 |
| Type | IDs |
|---|---|
| Synonymous | Lbcl2, Lsc |
| Gene |
UniProtKB-ID:
ARHG1_MOUSE,
E9PUF7_MOUSE
UniprotKB:
Q61210,
E9PUF7
UniParc:
UPI00000E898B,
UPI00005AD07A,
UPI00001C0371,
UPI00016118F2,
UPI00000291CA,
UPI00001C0370
EMBL:
BC012488,
U58203,
AC161441,
AK157056,
AY246273,
AK172354,
AY246272,
U89421,
AF314539
Ensembl:
ENSMUSG00000040940
KO:
mmu:16801
|
| Nucleutide sequences |
EMBL-CDS:
BAE42963.1,
BAE33947.1,
AAC52693.1,
AAC36527.1,
AAO91658.1,
AAG33860.1,
AAO91659.1,
AAH12488.1
Ensembl_TRS:
ENSMUST00000117419,
ENSMUST00000047873,
ENSMUST00000206508,
ENSMUST00000098683,
ENSMUST00000117796
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000146314,
ENSMUSP00000046469,
ENSMUSP00000096280,
ENSMUSP00000113366,
ENSMUSP00000113771
RefSeq:
XP_030098034.1,
NP_001123622.1,
XP_017177492.1,
NP_001123623.1,
XP_036008614.1,
XP_030098033.1,
XP_006539628.1,
NP_001123624.1,
NP_032514.1,
NP_001123625.1,
XP_030098035.1
|
| Others |
UniRef100:
UniRef100_Q61210,
UniRef100_E9PUF7
UniRef90:
UniRef90_E9PUF7,
UniRef90_Q61210
UniRef50:
UniRef50_Q92888-2,
UniRef50_Q92888-4
UniGene:
Mm.3181
CCDS:
CCDS85239.1,
CCDS52142.1,
CCDS52141.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员