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16635 Klra4

16635

Klra4

killer cell lectin-like receptor, subfamily A, member 4

protein-coding

Mus musculus

基因描述

Type Description
Definition killer cell lectin-like receptor, subfamily A, member 4

研究结论

Date Results Publications
2017-09-16 10:34:00 this study shows that after mouse cytomegalovirus infection, Ly49D augmented IFN-gamma production by virus-specific Ly49H(+) NK cells and preferentially promoted the generation of memory Ly49H(+) NK cells 27438766
2010-01-21 00:00:00 The MHC class I receptor Ly49D expressed on immature B cells recognizes MHC class I on peripheral tissues, inducing secretion of low levels of IFN-gamma and thereby down-regulating immature B cell homing to the lymph nodes or to sites of inflammation. 14568937
2010-01-21 00:00:00 The Ly49D activation receptor on mouse NK cells specifically recognizes the Chinese hamster histocompatibility class I molecule associated with Chinese hamster beta 2-microglobulin (beta 2m) and is not tolerized in murine beta 2m deficiency. 12077237
2010-01-21 00:00:00 Ly49D stimulation triggers cellular activation of CD4 and CD8 populations; Ly49D recognizes the classical hamster class I molecule Hm1-C4 on CHO cells, as demonstrated by the killing of Hm1-C4-transfected thymoma cells by Ly49D cytotoxic T cells. 19109149
2010-01-21 00:00:00 these data demonstrate that DAP10 does associate with Ly49H and Ly49D in primary NK cells. 19247984

名称对应

Type IDs
Synonymous Chok, Klra32, Klra33, Ly-49d, Ly49d, ly49r<129>
Gene
UniProtKB-ID: KLRA4_MOUSE, Q542S4_MOUSE
UniprotKB: Q60651, Q542S4
UniParc: UPI00000287F6, UPI0000004142
EMBL: AF218078, AF218079, U10090, AK145141, L78247, AK080171
Ensembl: ENSMUSG00000079852
KO: mmu:16635
Nucleutide sequences
EMBL-CDS: AAA50218.1, AAC32667.1, AAF99592.1, AAF99591.1, BAC37839.1, BAE26257.1
Ensembl_TRS: ENSMUST00000119096
Protein sequencees
Ensembl_PRO: ENSMUSP00000114004
RefSeq: XP_006505709.1, NP_034779.1, NP_001239506.1
Others
UniRef100: UniRef100_Q60651
UniRef90: UniRef90_Q60651
UniRef50: UniRef50_Q64329
UniGene: Mm.333431
CCDS: CCDS57457.1

全选

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