Type | Description |
---|---|
Definition | killer cell lectin-like receptor, subfamily A, member 4 |
Date | Results | Publications |
---|---|---|
2017-09-16 10:34:00 | this study shows that after mouse cytomegalovirus infection, Ly49D augmented IFN-gamma production by virus-specific Ly49H(+) NK cells and preferentially promoted the generation of memory Ly49H(+) NK cells | 27438766 |
2010-01-21 00:00:00 | The MHC class I receptor Ly49D expressed on immature B cells recognizes MHC class I on peripheral tissues, inducing secretion of low levels of IFN-gamma and thereby down-regulating immature B cell homing to the lymph nodes or to sites of inflammation. | 14568937 |
2010-01-21 00:00:00 | The Ly49D activation receptor on mouse NK cells specifically recognizes the Chinese hamster histocompatibility class I molecule associated with Chinese hamster beta 2-microglobulin (beta 2m) and is not tolerized in murine beta 2m deficiency. | 12077237 |
2010-01-21 00:00:00 | Ly49D stimulation triggers cellular activation of CD4 and CD8 populations; Ly49D recognizes the classical hamster class I molecule Hm1-C4 on CHO cells, as demonstrated by the killing of Hm1-C4-transfected thymoma cells by Ly49D cytotoxic T cells. | 19109149 |
2010-01-21 00:00:00 | these data demonstrate that DAP10 does associate with Ly49H and Ly49D in primary NK cells. | 19247984 |
Type | IDs |
---|---|
Synonymous | Chok, Klra32, Klra33, Ly-49d, Ly49d, ly49r<129> |
Gene |
UniProtKB-ID:
KLRA4_MOUSE,
Q542S4_MOUSE
UniprotKB:
Q60651,
Q542S4
UniParc:
UPI00000287F6,
UPI0000004142
EMBL:
AF218078,
AF218079,
U10090,
AK145141,
L78247,
AK080171
Ensembl:
ENSMUSG00000079852
KO:
mmu:16635
|
Nucleutide sequences |
EMBL-CDS:
AAA50218.1,
AAC32667.1,
AAF99592.1,
AAF99591.1,
BAC37839.1,
BAE26257.1
Ensembl_TRS:
ENSMUST00000119096
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000114004
RefSeq:
XP_006505709.1,
NP_034779.1,
NP_001239506.1
|
Others |
UniRef100:
UniRef100_Q60651
UniRef90:
UniRef90_Q60651
UniRef50:
UniRef50_Q64329
UniGene:
Mm.333431
CCDS:
CCDS57457.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
27438766 |
Immunity Tsukasa Nabekura , Lewis L Lanier |
2016-07-19 | - |
25921334 |
Proteomics Clin Appl Daniel Martins-de-Souza , Juliana S Cassoli , Juliana M Nascimento , Kenneth Hensley , Paul C Guest , Andres M Pinzon-Velasco , Christoph W Turck |
2015-10-01 | - |
23610400 |
Proc. Natl. Acad. Sci. U.S.A. Juan Liu , Shuxun Liu , Meng Xia , Sheng Xu , Chunmei Wang , Yan Bao , Minghong Jiang , Yue Wu , Tian Xu , Xuetao Cao |
2013-05-07 |
Ccr2,
Ccr5,
Tlr3,
Klra1,
Klra4,
Klrc1,
Tyrobp,
Klrk1,
Rhbdd3
|
23596445 |
Front Immunol Alan Rowe Schenkel , Luke C Kingry , Richard A Slayden |
2013-01-01 |
Klra1,
Klra10,
Klra12,
Klra13-ps,
Klra2,
Klra3,
Klra4,
Klra5,
Klra6,
Klra7,
Klra8,
Klra9,
Klra17,
Klra15,
Klra16,
Klra25,
Klra26,
Klra28,
Klra24,
Klra27,
Klra14-ps,
Klra11-ps,
Klra23,
Klra20,
Klra21,
Klra22,
Klra18,
Klra19
|
19247984 |
Eur. J. Immunol. Ilaria Tassi , Gaelle Le Friec , Susan Gilfillan , Toshiyuki Takai , Wayne M Yokoyama , Marco Colonna |
2009-04-01 |
Klra4,
Klra8,
Tyrobp,
Hcst
|
19109149 |
J. Immunol. Estelle Merck , Roger B Voyle , H Robson MacDonald |
2009-01-01 | - |
16141072 |
The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C Schönbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) |
2005-09-02 | - |
16141073 |
Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium |
2005-09-02 |
Gm14018,
Gm14964,
F630206G17Rik,
Oog3,
Notumos,
Ldlrap1,
Mdn1,
Pydc3,
9330171B17Rik,
Mfap1b,
Tmsb15b2,
Gm12802,
E430020m11rik,
Gm11335,
Gm15772,
Gm17762,
A930017K11Rik,
LOC100036513,
Gata5os,
Umad1,
Gm16982,
Gm9887,
Gm9872,
LOC100036530,
Gm9934,
Gm9913,
Gm11149,
BC028777,
Gm13999,
LOC100036540,
Gm9744,
Gm9983,
D630002J18Rik,
Gm16525,
Gm11696,
Dnajc3,
9430060I03Rik,
Gm12359,
4921516A02Rik,
Fam129c,
Gm10589,
Rsph3b,
Rnaset2a,
5430403G19Rik,
D030047H15Rik,
Gm13274,
B930046K06Rik,
Gm10862,
Gm10792,
Gm10802,
Gm10532,
G730003C15Rik,
Runx2os1,
Gm15612,
Gm10856,
Gm10857,
Gm10685,
Gm10803,
Gm10723,
F630028O10Rik,
Gm10836,
Gm10405,
Gm10513,
Gm10609,
F630201L12Rik,
4932427H20Rik,
Zfp389,
Gm10763,
Gm10062,
Gm10714,
Gm10531,
Gm10876,
Gm10750,
Gm10433,
Gm10837,
Gm10647,
Gm10648,
Gm10650,
Gm10610,
F830115B05Rik,
Gm10473,
Gm10614,
Gm10286,
G730046D07Rik,
Gm10287,
Gm10785,
Gm10183,
Gm10512,
1700061E17Rik,
Gm44113,
Gm10579,
Gm10741,
Gm10827,
Gm10522,
Gm10536,
Gm15998,
Faddos,
D130050E23Rik,
Gm10735
|
15084276 |
T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells. Immunity Michael J Townsend , Amy S Weinmann , Jennifer L Matsuda , Rachelle Salomon , Peggy J Farnham , Christine A Biron , Laurent Gapin , Laurie H Glimcher |
2004-04-01 |
Klra4,
Tbx21
|
14707119 |
Bone marrow allograft rejection mediated by a novel murine NK receptor, NKG2I. J. Exp. Med. Junzo Koike , Hiroshi Wakao , Yuko Ishizuka , Taka-aki Sato , Masaru Hamaoki , Ken-ichiro Seino , Haruhiko Koseki , Toshinori Nakayama , Masaru Taniguchi |
2004-01-05 |
Itga2,
Klra1,
Klra4,
Klrc1,
Klrc2,
Klrd1,
Klrb1c,
Klre1,
Klrk1,
Klrc3
|
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