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16627 Klra1

16627

Klra1

killer cell lectin-like receptor, subfamily A, member 1

protein-coding

Mus musculus

基因描述

Type Description
Definition killer cell lectin-like receptor, subfamily A, member 1

研究结论

Date Results Publications
2019-09-21 11:14:00 Most of the natural killer cell p46-related protein (NKp46) and NK cell Lectin-like receptor subfamily A (Ly49A) molecules were restricted to microdomains; however, individual NKp46 molecules resided in these domains for shorter periods and diffused faster on the surface of educated, compared to hyporesponsive, NK cells. 29440510
2013-01-26 10:39:00 study found the receptor Ly49A bound the MHC class I molecule H2-M3 with an affinity similar to its affinity for H-2D(d); specific recognition of H2-M3 by Ly49A regulated 'licensing' of NK cells and mediated 'missing-self' recognition of H2-M3-deficient bone marrow 23142773
2012-06-12 10:41:00 The difference in frequency of Ly49A-specific natural killer (NK) cells between H2-Dd+/+ and H2-Dd+/2 mice is reflected by a skewed balance between proliferation and apoptosis in this subset. 22287714
2010-05-31 12:09:00 Overexpression of Ly49A enhanced the tumor killing activity of mouse lymphocytes. 11877077
2010-01-21 00:00:00 The repertoire of inhibitory Ly49 receptors may be formed under the influenced of Fyn-dependent NK cell activation as well as the respective MHC class I environment. 11870621

名称对应

Type IDs
Synonymous A1, CH29-493D4.3, Klra22, Ly49a, Ly49o<129>, Ly49v
Gene
UniProtKB-ID: Q8MHR8_MOUSE
UniprotKB: Q8MHR8
UniParc: UPI0000023404
EMBL: AC087336, AK080158, AY078436
Ensembl: ENSMUSG00000079853
KO: mmu:16627
Nucleutide sequences
EMBL-CDS: BAC37835.1, AAL78064.1
Ensembl_TRS: ENSMUST00000032288
Protein sequencees
Ensembl_PRO: ENSMUSP00000032288
RefSeq: NP_057868.2
Others
UniRef100: UniRef100_Q8MHR8
UniRef90: UniRef90_P20937
UniRef50: UniRef50_Q64329
UniGene: Mm.24399, Mm.333431

全选

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