| Type | Description |
|---|---|
| Definition | integrin beta 7 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:02:00 | Abnormal Peyer patch development and B-cell gut homing drive IgA deficiency in Kabuki syndrome. | 31816409 |
| 2019-03-23 11:57:00 | Transmission of integrin beta7 transmembrane domain topology enables gut lymphoid tissue development. | 29535192 |
| 2019-03-09 12:36:00 | lack of beta7 integrin significantly impairs tumor growth without affecting tumor frequencies, with a mild translatable effect on overall survival. | 30235302 |
| 2018-03-24 12:00:00 | Loss of MAdCAM-1 has beneficial effects regarding the development of NASH - manifested by reduced hepatic oxidative stress and decreased inflammation. In contrast, beta7-Integrin-deficiency results in increased steatohepatitis. | 28192190 |
| 2017-10-21 12:03:00 | AEbeta7 is of key relevance for gut trafficking of inflammatory bowel disease (IBD) CD8(+) T cells and CD4(+) Th9 cells in vivo and mainly retention might account for this effect. These findings indicate that blockade of alphaEbeta7 in addition to alpha4beta7 may be particularly effective in intestinal disorders with expansion of CD8(+) and Th9 cells such as IBD. | 27543429 |
| Type | IDs |
|---|---|
| Synonymous | Ly69 |
| Gene |
UniProtKB-ID:
ITB7_MOUSE
UniprotKB:
P26011
UniParc:
UPI0000001906
EMBL:
S63504,
S44607,
BC011184,
AK078871,
M68903,
M95632,
M95633,
AK154766,
AK155207
Ensembl:
ENSMUSG00000001281
KO:
mmu:16421
|
| Nucleutide sequences |
EMBL-CDS:
AAA02749.1,
AAA39324.1,
BAE33119.1,
BAE32815.1,
AAB27396.1,
AAH11184.1,
BAC37433.1,
AAA39323.1,
AAB23193.1
Ensembl_TRS:
ENSMUST00000001327
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000001327
RefSeq:
XP_006520545.1,
XP_017171929.1,
NP_038594.2
|
| Others |
UniRef100:
UniRef100_P26011
UniRef90:
UniRef90_P26011
UniRef50:
UniRef50_P26010
UniGene:
Mm.58
CCDS:
CCDS49740.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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