| Type | Description |
|---|---|
| Definition | Vpu |
| Date | Results | Publications |
|---|---|---|
| 2020-12-26 13:11:00 | The viral protein U (Vpu)-interacting host protein ATP6V0C down-regulates cell-surface expression of tetherin and thereby contributes to HIV-1 release. | 32291285 |
| 2020-11-21 13:33:00 | Differential Vpu-Mediated CD4 and Tetherin Downregulation Functions among Major HIV-1 Group M Subtypes. | 32376625 |
| 2020-09-19 16:26:00 | HIV-1 Vpu Downregulates Tim-3 from the Surface of Infected CD4(+) T Cells. | 31941771 |
| 2020-03-28 10:04:00 | In summary, these findings demonstrate that HIV-1 Vpu potently suppresses NF-kappaB-elicited antiviral immune responses at the transcriptional level. | 30717826 |
| 2019-07-06 12:03:00 | this study shows that the activation of the pathway by IFN-alpha stimulation is disrupted by HIV proteins Vpu and Nef, which both reduce IFN-alpha induction of phosphorylation | 30282499 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
Q9WB91_HV1H2
UniprotKB:
Q9WB91
UniParc:
UPI0000102A6C
EMBL:
AF033819
KO:
vg:155945
|
| Nucleutide sequences |
EMBL-CDS:
AAD20388.1
|
| Protein sequencees |
RefSeq:
NP_057855.1
|
| Others |
UniRef100:
UniRef100_P05919
UniRef90:
UniRef90_P05919
UniRef50:
UniRef50_P05919
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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||||
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