| Type | Description |
|---|---|
| Definition | GLI pathogenesis related 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-09-16 10:56:00 | Here, sequence analyses, structural modeling, mutagenesis combined with pull-down assays, X-ray crystal structure determination and small-angle X-ray scattering were used to investigate the Beclin 1-GAPR-1 interaction. changes in the structure of the equatorial groove combined with the improved dimerization of pentad mutant GAPR-1 are likely to abrogate binding to Beclin 1. | 28876241 |
| 2017-01-14 11:19:00 | This study identified a previously unrecognized role for GAPR-1 to control a unifying TLR4 signaling complex and to regulate type I Interferon signaling activation. | 26678074 |
| 2014-08-09 12:17:00 | Hypoxia promotes epithelial-mesenchymal transition of hepatocellular carcinoma cells via inducing GLIPR-2 expression. | 24204846 |
| 2013-09-21 10:47:00 | GLIPR-2 overexpression in HK-2 cells can potentiate EMT-like processes in this cell type through the ERK1/2 signaling pathway | 23516513 |
| 2013-04-06 13:03:00 | the charge properties of the lipid bilayer can regulate GAPR-1 dynamics as a potential mechanism to modulate GAPR-1 function | 22560898 |
| Type | IDs |
|---|---|
| Synonymous | C9orf19, GAPR-1, GAPR1 |
| Gene |
UniProtKB-ID:
GAPR1_HUMAN,
A0A087WUM5_HUMAN,
Q5VZR0_HUMAN,
A0A088AWP7_HUMAN
UniprotKB:
Q9H4G4,
A0A087WUM5,
Q5VZR0,
A0A088AWP7
UniParc:
UPI000045889E,
UPI0003C5712A,
UPI0000417BF3,
UPI000006DF50
EMBL:
AK075091,
AL158830,
AK074488,
AY039756,
AJ011129,
BC017918
Ensembl:
ENSG00000122694
KO:
hsa:152007
|
| Nucleutide sequences |
EMBL-CDS:
AAK83460.1,
BAC11019.1,
AAH17918.1,
CAC12812.1,
BAC11395.1
Ensembl_TRS:
ENST00000377960,
ENST00000619700,
ENST00000377959,
ENST00000396613
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000367196,
ENSP00000478768,
ENSP00000367195,
ENSP00000379857
RefSeq:
NP_001273941.1,
XP_024303184.1,
NP_001273942.1,
NP_001273943.1,
NP_001273940.1,
NP_001273939.1,
NP_071738.1
|
| Others |
UniRef100:
UniRef100_Q5VZR0,
UniRef100_A0A088AWP7,
UniRef100_A0A087WUM5,
UniRef100_Q9H4G4
UniRef90:
UniRef90_A0A2I3NDY8,
UniRef90_M3WHJ5,
UniRef90_Q9H4G4,
UniRef90_A0A2I3LLX9
UniRef50:
UniRef50_A0A2I3NDY8,
UniRef50_M3WHJ5,
UniRef50_A0A2I3LLX9,
UniRef50_Q9H4G4
UniGene:
Hs.493819
CCDS:
CCDS6598.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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