| Type | Description |
|---|---|
| Definition | hyaluronan synthase 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-09 11:44:00 | allergen-challenged mice that overexpress HAS2 in myofibroblasts and smooth muscle cells develop increased airway fibrosis, which lessens airway hyperresponsiveness to bronchoconstrictors. | 28787175 |
| 2017-08-05 10:42:00 | Expression of the innate immune receptor Toll-like receptor 4 (TLR4) and the extracellular matrix glycosaminoglycan hyaluronan (HA) on type 2 alveolar epithelial cells (AEC@2) are important for AEC2 renewal, repair of lung injury and limiting the extent of fibrosis. Either deletion of TLR4 or HA synthase 2 in surfactant-protein-C-positive AEC2s leads to impaired renewal capacity, severe fibrosis and mortality. | 27694932 |
| 2017-05-27 10:26:00 | Has2 mRNA was expressed in the surrounding mesenchyme from E12.0 to 18.0 in both molar and incisor tooth germs, but disappeared after birth. | 27289075 |
| 2016-09-03 10:55:00 | the ineffective repair of injured cartilage in Has1(-/-) joints can be at least partly explained by the markedly enhanced expression of particular genes in pathways linked to ECM turnover, IL-17/IL-6 cytokine signaling, and apoptosis. | 26521733 |
| 2016-06-11 10:45:00 | these results highlight the role of nSMase2 in apoptosis evoked by nutrient starvation that could contribute to the delayed apoptosis of hypertrophic chondrocytes in the growth plate, and emphasize the antiapoptotic properties of HAS2 | 25555205 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
HYAS2_MOUSE
UniprotKB:
P70312
UniParc:
UPI0000004140
EMBL:
AK079729,
U69695,
CH466545,
U53222,
U52524,
BC080281
Ensembl:
ENSMUSG00000022367
KO:
mmu:15117
|
| Nucleutide sequences |
EMBL-CDS:
AAC53309.2,
EDL29280.1,
AAB17609.1,
AAH80281.1,
AAC52651.1,
BAC37733.1
Ensembl_TRS:
ENSMUST00000050544
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000062212
RefSeq:
NP_032242.3
|
| Others |
UniRef100:
UniRef100_P70312
UniRef90:
UniRef90_P70312
UniRef50:
UniRef50_P70312
UniGene:
Mm.5148
CCDS:
CCDS27480.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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