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14991 H2-M3

14991

H2-M3

histocompatibility 2, M region locus 3

protein-coding

Mus musculus

基因描述

Type Description
Definition histocompatibility 2, M region locus 3

研究结论

Date Results Publications
2013-01-26 10:39:00 study found the receptor Ly49A bound the MHC class I molecule H2-M3 with an affinity similar to its affinity for H-2D(d); specific recognition of H2-M3 by Ly49A regulated 'licensing' of NK cells and mediated 'missing-self' recognition of H2-M3-deficient bone marrow 23142773
2011-01-29 10:50:00 Similar to H2-M3-restricted CD8-positive T cells, CD8+ T cells restricted to other major histocompatibility class Ib molecules are able to undergo extensive proliferation after primary infection with Listeria monocytogenes. 21098224
2010-01-21 00:00:00 H2-M3-restricted CD8+ T cells contribute to protective immunity against intracellular bacterial pathogen Chlamydia pneumoniae. 17785832
2010-01-21 00:00:00 Activation and proliferation of M3-restricted CD8+ T cells is not required for protective immunity against Listeria monocytogenes 16461341
2010-01-21 00:00:00 MHC class Ia-restricted responses cannot compensate for H2-M3-mediated immunity; a nonredundant role of H2-M3 is suggested in protective immunity against Listeria monocytogenes. 16476767

名称对应

Type IDs
Synonymous H-2M3, Hmt, M3a, MuprM3, MuprM301, MuprM302, R4B2
Gene
UniProtKB-ID: Q31093_MOUSE
UniprotKB: Q31093
UniParc: UPI0000027ECF
EMBL: U18797, CT033782
Ensembl: ENSMUSG00000016206
KO: mmu:14991
Nucleutide sequences
EMBL-CDS: AAA60335.1
Ensembl_TRS: ENSMUST00000038580
Protein sequencees
Ensembl_PRO: ENSMUSP00000035687
RefSeq: NP_038847.1, XP_036016220.1
Others
UniRef100: UniRef100_Q31093
UniRef90: UniRef90_Q31093
UniRef50: UniRef50_P06339
UniGene: Mm.14437

全选

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研究热度

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