| Type | Description |
|---|---|
| Definition | transcriptional activator |
| Date | Results | Publications |
|---|---|---|
| 2017-10-21 10:54:00 | Data suggest MHV68 RTA specifically recognizes and recruits activated (phosphorylated at Tyr705) host Stat3 during lytic phase of infection; Stat3, once phosphorylated at Tyr705, avidly binds consensus target site in promoters of regulated genes. (MHV68 = murine gammaherpesvirus 68; RTA = replication and transcription activator coded for by ORF50; Stat3 = signal transducer and activator of transcription 3 protein) | 28821622 |
| 2016-03-12 11:02:00 | Epigenetic modification of Rta (ORF50) promoter is not responsible for virus reactivation. | 26666189 |
| 2015-08-01 12:02:00 | This study identified ORF48 as an RTA-responsive gene and showed that ORF48 is important for Murine herpesvirus 68 replication both in vitro and in vivo. | 25762743 |
| 2012-03-24 10:30:00 | Murine gammaherpesvirus 68 subverts early NF-kappaB activation and cytokine production through vrial RTA-induced RelA degradation. | 22130545 |
| 2012-02-25 10:07:00 | ORF49 promotes viral replication and is a derepressor for RTA. | 22090108 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
P88988_MHV68
UniprotKB:
P88988
UniParc:
UPI00000F6CED
EMBL:
U97553,
Y09060
KO:
vg:1497167
|
| Nucleutide sequences |
EMBL-CDS:
CAA70265.1,
AAB66410.1
|
| Protein sequencees |
RefSeq:
NP_044887.3
|
| Others |
UniRef100:
UniRef100_Q9QAI4
UniRef90:
UniRef90_Q9QAI4
UniRef50:
UniRef50_Q9QAI4
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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