| Type | Description |
|---|---|
| Definition | NLR family pyrin domain containing 4 |
| Date | Results | Publications |
|---|---|---|
| 2019-06-08 12:05:00 | NLRP4 binds ARHGDIA (Rho GDP dissociation inhibitor alpha) to regulate Rho GTPase signaling and facilitate actin-mediated xenophagy. | 29099277 |
| 2019-02-02 11:25:00 | The minor allele of rs16986718G > A in NLRP4 may be a genetic marker that predicts asthma exacerbation in adult asthmatics who smoke. | 30526007 |
| 2018-03-31 10:23:00 | NLRP4 is an important mediator of cardiac remodeling in vitro and in vivo. | 28486191 |
| 2015-10-17 10:24:00 | This study describes conformational stability of native NLRP14 and mutants in their monomeric and dimeric states and compares them to NLRP4, a representative of a native pyrin domain fold. | 25403012 |
| 2015-06-27 10:59:00 | Findings suggest that NLR family pyrin domain containing 2 (NLRP2P) is a processed pseudogene that regulates NF-kappaB RelA/p65 activity and thus represents the newest member of the POP family, pyrin-only protein 4 (POP4; NLRP4). | 24871464 |
| Type | IDs |
|---|---|
| Synonymous | CLR19.5, CT58, NALP4, PAN2, PYPAF4, RNH2 |
| Gene |
UniProtKB-ID:
NALP4_HUMAN,
B2RCA1_HUMAN
UniprotKB:
Q96MN2,
B2RCA1
UniParc:
UPI000013E6FD,
UPI0000169F72,
UPI000175085C,
UPI00001A8B6B
EMBL:
BC016443,
AK056688,
AK315003,
AY072792,
AF482706,
BC050326,
AF442488,
AF479747
Ensembl:
ENSG00000160505
KO:
hsa:147945
|
| Nucleutide sequences |
EMBL-CDS:
AAL87104.1,
AAL88672.1,
AAH50326.1,
AAL68396.1,
AAH16443.1,
AAL35293.1,
BAB71254.1,
BAG37498.1
Ensembl_TRS:
ENST00000587891,
ENST00000301295
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000301295,
ENSP00000465463
RefSeq:
NP_604393.2,
XP_016881833.1,
XP_016881834.1
|
| Others |
UniRef100:
UniRef100_B2RCA1,
UniRef100_Q96MN2
UniRef90:
UniRef90_Q96MN2
UniRef50:
UniRef50_Q96MN2
UniGene:
Hs.631533
CCDS:
CCDS12936.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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