| Type | Description |
|---|---|
| Definition | SIX homeobox 5 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-02 11:07:00 | the higher expressions of SIX1-5 were associated with the greater possibility of the tumorigenesis in lung neoplasms | 27821176 |
| 2015-10-17 10:09:00 | Three causative genes for BOR syndrome have been reported thus far: EYA1, SIX1, and SIX5, but the causative genes for approximately half of all BOR patients remain unknown.[review] | 24730701 |
| 2012-07-14 11:23:00 | In East Asian populations, a SIX1 mutation has been reported in a Japanese family with branchio-oto (BO) syndrome,yet SIX5 mutations have never been reported. | 22447252 |
| 2011-03-26 10:23:00 | Study reports a screening of 140 patients from 124 families with Branchio-oto-renal and identified 36 EYA1 mutations in 42 unrelated patients, 2 mutations, and 1 change of unknown significance in SIX1 in 3 unrelated patients, but no mutation in SIX5. | 21280147 |
| 2010-04-07 21:40:00 | Observational study of gene-disease association. (HuGE Navigator) | 20198315 |
| Type | IDs |
|---|---|
| Synonymous | BOR2, DMAHP |
| Gene |
UniProtKB-ID:
SIX5_HUMAN
UniprotKB:
Q8N196
UniParc:
UPI0000366E2B
EMBL:
BC033204,
AK074826,
BU859227,
AC074212,
X84813
Ensembl:
ENSG00000177045
KO:
hsa:147912
|
| Nucleutide sequences |
EMBL-CDS:
AAH33204.1
Ensembl_TRS:
ENST00000317578
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000316842
RefSeq:
NP_787071.3
|
| Others |
UniRef100:
UniRef100_Q8N196
UniRef90:
UniRef90_Q8N196
UniRef50:
UniRef50_Q8N196
UniGene:
Hs.43314
CCDS:
CCDS12673.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 27821176 |
The expression profile and clinic significance of the SIX family in non-small cell lung cancer. J Hematol Oncol Qian Liu , Anping Li , Yijun Tian , Yu Liu , Tengfei Li , Cuntai Zhang , Jennifer D Wu , Xinwei Han , Kongming Wu |
2016-11-08 | - |
| 25609649 |
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. Mol. Syst. Biol. Xu Li , Wenqi Wang , Jiadong Wang , Anna Malovannaya , Yuanxin Xi , Wei Li , Rudy Guerra , David H Hawke , Jun Qin , Junjie Chen |
2015-01-01 |
ABI1,
ZBTB33,
TCF24,
RPL29P11,
FOXO6,
HDAC6,
HDAC5,
MEF2B,
CHAF1A,
PARP2,
HMGXB4,
SMC4,
FARSB,
HUWE1,
RAD50,
SUGP2,
ABI2,
WASF2,
ALYREF,
TSHZ1,
DDX39A,
TRIB1,
GPHN,
AKAP8,
STAG1,
SF3A1,
TNIP1,
ADAR,
HMG20B,
IRF9,
MYL12B,
MYL9,
CFDP1,
MCRS1,
TOMM40,
CDX2,
COG5,
HOXB13,
LRRC41,
NCOA2,
CEBPB,
KAT5,
SLU7,
DRAP1,
SMC2,
CENPB,
PRPF8,
MXD4,
P3H4,
TRIM3,
ARID3B,
STAG2,
NCKAP1,
IQGAP2,
ZNF268,
UTP14A,
MRPS30,
BRD8,
TCERG1,
MORF4,
POP1,
SF3A3,
SF3B2,
KIF2C,
ATF7,
TMED1,
RCC1,
DDX52,
CHD4,
FOXN3,
PSIP1,
WDHD1,
CHI3L2,
BAZ1A,
NISCH,
CHEK2,
MRPL3,
PNKP,
SGF29,
NACC1,
ACOT7,
LACTB,
DNTTIP1,
FOXP4,
IKBIP,
JDP2,
ANKRD26P1,
HEXIM2,
C17orf49,
NDUFA11,
PUSL1,
COPA,
MAP3K8,
LIN54,
C5orf24,
COX7A2,
CPOX,
CPS1,
NACC2
|
| 24730701 |
Branchio-oto-renal syndrome: comprehensive review based on nationwide surveillance in Japan. Pediatr Int Naoya Morisada , Kandai Nozu , Kazumoto Iijima |
2014-06-01 |
SIX5,
EYA1,
SIX1
|
| 22939629 |
A census of human soluble protein complexes. Cell Pierre C Havugimana , G Traver Hart , Tamás Nepusz , Haixuan Yang , Andrei L Turinsky , Zhihua Li , Peggy I Wang , Daniel R Boutz , Vincent Fong , Sadhna Phanse , Mohan Babu , Stephanie A Craig , Pingzhao Hu , Cuihong Wan , James Vlasblom , Vaqaar-un-Nisa Dar , Alexandr Bezginov , Gregory W Clark , Gabriel C Wu , Shoshana J Wodak , Elisabeth R M Tillier , Alberto Paccanaro , Edward M Marcotte , Andrew Emili |
2012-08-31 |
SRB2,
TRA1,
MED6,
CDH2,
DDTL,
ABI1,
SRA1,
UQCRFS1P1,
SNRPGP15,
ZNF316,
LOC100132057,
PDCD6IP,
PDCD6,
MED16,
PIGK,
WASH1,
CHAF1A,
TOM1L1,
HMGXB4,
RANBP9,
SMC4,
UBA2,
SAE1,
FARSB,
ABCB6,
ABCF2,
TIMM23B,
SCAMP3,
DPP3,
HUWE1,
TSSC4,
PDCD7,
USH1C,
PQBP1,
ARPC5,
ARPC4,
ARPC3,
ARPC1B,
ACTR3,
ACTR2,
NUBP2,
TSFM,
PPIF,
ARPC2,
RAD50,
PREB,
ACTR1B,
ACTR1A,
RASGRP1,
LRPPRC,
PDIA6,
TRAP1,
RBM12,
G3BP1,
SUGP2,
TRIM28,
WASF2,
SLC25A13,
SORBS3,
ALYREF,
TXNDC9,
CDK4,
PRMT3,
PSME3,
MPHOSPH6,
CDK5,
NUTF2,
EIF1,
FLOT1,
PSMD14,
CDK7,
ADAM10,
PLIN3,
STX6,
MSLN,
HNRNPR,
MRPS31,
TIMM17B,
RIDA,
POP7,
SRRM1,
CDK9,
STAM2,
SF3B4,
ZMPSTE24,
STUB1,
UBE4B,
BET1,
CWC27,
SAP18,
SMNDC1,
BCAS2,
EIF1B,
SF3A1,
MAEA,
KATNB1,
TCIRG1,
RTN3,
LANCL1
|
| 22447252 |
Laryngoscope Shih-Hao Wang , Chen-Chi Wu , Ying-Chang Lu , Yin-Hung Lin , Yi-Ning Su , Wuh-Liang Hwu , I-Shing Yu , Chuan-Jen Hsu |
2012-05-01 |
SIX5,
EYA1,
SIX1
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21280147 |
Hum. Mutat. Pauline Krug , Vincent Morinière , Sandrine Marlin , Valérie Koubi , Heinz D Gabriel , Estelle Colin , Dominique Bonneau , Rémi Salomon , Corinne Antignac , Laurence Heidet |
2011-02-01 |
SIX5,
EYA1,
SIX1
|
| 20198315 |
Association of genetic variants with hemorrhagic stroke in Japanese individuals. Int. J. Mol. Med. Tetsuro Yoshida , Kimihiko Kato , Kiyoshi Yokoi , Mitsutoshi Oguri , Sachiro Watanabe , Norifumi Metoki , Hidemi Yoshida , Kei Satoh , Yukitoshi Aoyagi , Yoshinori Nozawa , Yoshiji Yamada |
2010-04-01 | - |
| 19851296 |
Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. Am. J. Hypertens. Mitsutoshi Oguri , Kimihiko Kato , Kiyoshi Yokoi , Tetsuro Yoshida , Sachiro Watanabe , Norifumi Metoki , Hidemi Yoshida , Kei Satoh , Yukitoshi Aoyagi , Yoshinori Nozawa , Yoshiji Yamada |
2010-01-01 |
CDH4,
CDH15,
FAM13A,
EMC8,
PITRM1,
CCT2,
SEPT9,
CPLX2,
ALDH1L1,
RUVBL2,
TSPAN9,
USP20,
DIDO1,
ACOT7,
CHUK,
ZNF618,
GYLTL1B,
CDYL2,
COL4A1,
COL6A3,
COL13A1,
COX5B,
CST2,
SIX5,
CTBP1,
ZSWIM2,
FAM19A4,
PNLDC1,
DBH,
MARCH10,
ACE,
TRDMT1,
DOCK1,
F10,
SDK1,
ZFP30,
MON1B,
WDR37,
FOXF1,
TCF25,
DIP2C,
CUL9,
ZC3H3,
NUP210,
PACS2,
CAMTA1,
CLEC16A,
SUN1,
SLC7A8,
ALOX5,
FUT7,
SS18L1,
GPR160,
EIF2AK1,
BIN1,
UHRF1,
OSGIN1,
NDST1,
ADAMTSL5,
IRF5,
ITPK1,
IVD,
LAMA3,
LLGL2,
LRP5,
LRPAP1,
LTBP2,
MCC,
MEF2D,
ARVCF,
ABCC1,
MYH9,
MYO7B,
PPP1R12B,
ROR2,
NVL,
PLA2G3,
IL21R,
ATL1,
POLR1D,
PCSK2,
SPTBN5,
PECAM1,
PML,
TOLLIP,
PIGG,
UBE2R2,
NADSYN1,
TMEM39A,
OGDHL,
UGGT2,
PRKCQ,
PRKG1,
PANX2,
PSMA4,
PSMB4,
ATP10A,
ERGIC1,
JPH3
|
| 19274049 |
A census of human transcription factors: function, expression and evolution. Nat Rev Genet Juan M Vaquerizas , Sarah K Kummerfeld , Sarah A Teichmann , Nicholas M Luscombe |
2009-04-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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