| Type | Description |
|---|---|
| Definition | chondroitin sulfate proteoglycan 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 12:34:00 | High NG2 expression is associated with glioblastoma. | 30590711 |
| 2020-03-07 11:34:00 | We observed familial segregation of two rare missense mutations in Chondroitin Sulfate Proteoglycan 4 (CSPG4) (c.391G > A [p.A131T], MAF 7.79 x 10(-5) and c.2702T > G [p.V901G], MAF 2.51 x 10(-3)). The CSPG4(A131T) mutation was absent from the Swedish Schizophrenia Exome Sequencing Study (2536 cases, 2543 controls), while the CSPG4(V901G) mutation was nominally enriched in cases (11 cases vs. 3 controls) | 29302076 |
| 2019-02-09 12:39:00 | Ng2/Cspg4 deletion altered the expression of genes regulating cell proliferation and apoptosis. | 29196603 |
| 2019-02-02 11:21:00 | Study suggests that CSPG4 and progranulin may engage in mutual cell-to-cell communications orchestrating regenerative processes, which may enhance the repair capacity of the adult brain. CSPG4 might engage with PTPRs as cell bound ligand or as soluble molecule after its shedding, possibly regulating thereby adhesion and synaptic strength, which contribute to the rebuilding of connectivity after injury. [review] | 29054751 |
| 2019-01-05 10:44:00 | NG2/CSPG4 expression has been demonstrated in oligodendrogliomas, astrocytomas, and glioblastomas (GB), and it correlates with malignancy | 30213051 |
| Type | IDs |
|---|---|
| Synonymous | HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2 |
| Gene |
UniProtKB-ID:
CSPG4_HUMAN
UniprotKB:
Q6UVK1
UniParc:
UPI00001AEEB6
EMBL:
AY359468,
CH471136,
AC105020,
X96753
Ensembl:
ENSG00000173546
KO:
hsa:1464
|
| Nucleutide sequences |
EMBL-CDS:
EAW99240.1,
AAQ62842.1,
CAA65529.1,
EAW99239.1
Ensembl_TRS:
ENST00000308508
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000312506
RefSeq:
NP_001888.2
|
| Others |
UniRef100:
UniRef100_Q6UVK1
UniRef90:
UniRef90_Q6UVK1
UniRef50:
UniRef50_Q8VHY0
UniGene:
Hs.513044
CCDS:
CCDS10284.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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