| Type | Description |
|---|---|
| Definition | proline rich membrane anchor 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-25 11:25:00 | PRIMA-1 can rescue amyloid-state p53 mutants | 30602570 |
| 2018-08-04 10:56:00 | Methylation of SFRP1, SFRP2, SDC2, and PRIMA1 promoter sequences was observed in 85.1%, 72.3%, 89.4%, and 80.9% of plasma samples from patients with Colorectal cancer and 89.2%, 83.8%, 81.1% and 70.3% from adenoma patients, respectively. | 28753106 |
| 2018-03-24 12:01:00 | PRIMA-1 could cause the demethylation of TP73, through DNMT1 depletion, to subsequently enhance the unfolded protein response | 27533450 |
| 2018-01-13 13:13:00 | Silencing of CD24 enhanced restoration of PRIMA-1-induced mutant p53 in endogenous TP53(P223L/V274F) DU145 cells. | 26712693 |
| 2016-10-22 11:03:00 | The results suggest that aberrant methylation of rDNA and PRIMA1 is associated with the pathogenesis of Borderline Personality Disorder. | 26742039 |
| Type | IDs |
|---|---|
| Synonymous | PRIMA |
| Gene |
UniProtKB-ID:
PRIMA_HUMAN,
A0A024R6J9_HUMAN
UniprotKB:
Q86XR5,
A0A024R6J9
UniParc:
UPI0000051D0A,
UPI0000051D1C
EMBL:
CH471061,
AY225517,
AY225516
Ensembl:
ENSG00000175785,
ENSG00000274089
KO:
hsa:145270
|
| Nucleutide sequences |
EMBL-CDS:
AAO74854.1,
AAO74853.1,
EAW81532.1,
EAW81534.1
Gene_ORFName:
hCG_1658529
Ensembl_TRS:
ENST00000617019,
ENST00000629961,
ENST00000393140,
ENST00000627063,
ENST00000316227,
ENST00000393143,
ENST00000477603,
ENST00000611347
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000376848,
ENSP00000486953,
ENSP00000376851,
ENSP00000434370,
ENSP00000320948,
ENSP00000486875,
ENSP00000479082,
ENSP00000479855
RefSeq:
XP_024305250.1,
NP_821092.1,
XP_011534758.1
|
| Others |
UniRef100:
UniRef100_Q86XR5
UniRef90:
UniRef90_Q86XR5
UniRef50:
UniRef50_D3ZZP4
UniGene:
Hs.432401
CCDS:
CCDS9912.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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