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143689 PIWIL4

143689

PIWIL4

piwi like RNA-mediated gene silencing 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition piwi like RNA-mediated gene silencing 4

研究结论

Date Results Publications
2020-10-31 13:19:00 PIWIL4 Maintains HIV-1 Latency by Enforcing Epigenetically Suppressive Modifications on the 5' Long Terminal Repeat. 32161174
2018-12-29 10:40:00 these findings revealed that Piwil4 is a novel regulator of ER signaling that could be targeted to inhibit breast cancer growth and migration. 30226541
2018-02-24 11:43:00 Results revealed that Piwil4 exhibits lower expression in the cell nucleus than in the cytoplasm. Along with nuclear location of PIWIL2, PIWIL4 expression is associated with worse prognosis of hepatocellular carcinoma. 27894076
2017-11-04 12:02:00 HIWI2 is aberrantly expressed in cells of the Retinoblastoma (RB) line (Y79) and silencing of HIWI2 downregulates OTX2, suggesting that HIWI2 might affects cell cycle and plays a role in the progression of RB. 28861107
2017-10-21 11:14:00 data delineate MIWI2-dependent functions outside of the germline and demonstrate the presence of distinct subsets of airway multiciliated cells that can be discriminated by MIWI2 expression. 28920925

名称对应

Type IDs
Synonymous HIWI2, MIWI2
Gene
UniProtKB-ID: PIWL4_HUMAN, A0A140VKG8_HUMAN
UniprotKB: Q7Z3Z4, A0A140VKG8
UniParc: UPI000006D0EC, UPI0000E4457A, UPI00017A6D5E
EMBL: AB079366, BC031060, AK293616, HM005708, AK096837, AK093475, CH471065, CR749642
Ensembl: ENSG00000134627
KO: hsa:143689
Nucleutide sequences
EMBL-CDS: BAC04873.1, CAH18436.1, BAC81341.1, BAG57076.1, BAC04179.1, AAH31060.1, EAW66940.1, AEE61305.1
Gene_ORFName: hCG_1817581
Ensembl_TRS: ENST00000446230, ENST00000543336, ENST00000299001
Protein sequencees
Ensembl_PRO: ENSP00000299001, ENSP00000444575, ENSP00000413838
RefSeq: NP_689644.2
Others
UniRef100: UniRef100_Q7Z3Z4
UniRef90: UniRef90_Q7Z3Z4
UniRef50: UniRef50_Q9JMB7
UniGene: Hs.660188
CCDS: CCDS31656.1

全选

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