| Type | Description |
|---|---|
| Definition | Fyn proto-oncogene |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 19:06:00 | Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on calcium. | 31452242 |
| 2020-04-18 10:04:00 | In vivo experiments using A53T and viral-alphaSyn overexpression mouse models as well as human Parkinson's disease neuropathological results further confirm the role of Fyn in NLRP3 inflammasome activation. | 31036561 |
| 2020-02-29 11:30:00 | Tau controls the nanoscale organization of Fyn in dendrites, with the pathological Tau P301L mutation potentially contributing to synaptic dysfunction by promoting aberrant Fyn nanoclustering in spines. | 31237563 |
| 2019-11-16 12:01:00 | Fyn(-/-) mice exhibit reduced Tyr-phosphorylation of EPO-R and decreased Fyn(-/-) mice responded poorly to stress erythropoiesis. Absence of Fyn resulted in persistent-activation of Nrf2, accumulation of nonfunctional proteins, over-activation of Jak2-Akt-mTOR-pathway, and repression of autophagy with perturbation of lysosomal-clearance. | 30252956 |
| 2019-10-26 11:34:00 | Our results suggest that Fyn-mediated regulation of the cell-cell adhesion of neuroblasts is critical for their detachment from chains in the postnatal brain | 29661967 |
| Type | IDs |
|---|---|
| Synonymous | AI448320, AW552119 |
| Gene |
UniProtKB-ID:
FYN_MOUSE
UniprotKB:
P39688
UniParc:
UPI0000021753,
UPI0000196525
EMBL:
U70324,
BC032149,
M27266,
AK171646,
BC092217,
AK156584
Ensembl:
ENSMUSG00000019843
KO:
mmu:14360
|
| Nucleutide sequences |
EMBL-CDS:
BAE33766.1,
BAE42585.1,
AAH92217.1,
AAA37644.1,
AAH32149.1,
AAB09568.1
Ensembl_TRS:
ENSMUST00000063091,
ENSMUST00000135242,
ENSMUST00000126486,
ENSMUST00000099967,
ENSMUST00000146287
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000114188,
ENSMUSP00000115233,
ENSMUSP00000057707,
ENSMUSP00000097547,
ENSMUSP00000117111
RefSeq:
XP_036011504.1,
XP_006512603.1,
NP_001116365.1,
NP_001116364.1,
XP_036011499.1,
XP_036011503.1,
XP_036011502.1,
XP_006512602.1,
XP_036011501.1,
XP_036011506.1,
XP_036011507.1,
XP_030100741.1,
XP_011241419.1,
XP_036011505.1,
XP_036011500.1,
NP_032080.2,
XP_036011497.1,
XP_036011496.1,
XP_036011498.1
|
| Others |
UniRef100:
UniRef100_P39688
UniRef90:
UniRef90_P06241
UniRef50:
UniRef50_P06241
UniGene:
Mm.4848
CCDS:
CCDS23788.1,
CCDS48538.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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