| Type | Description |
|---|---|
| Definition | citrate synthase |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 12:40:00 | The active sites of the citrate synthase is almost identical, the differences in reactions catalyzed by citrate synthase are caused by residues that are in the vicinity of the active site and influence conformational changes of the citrate synthase. | 31141475 |
| 2018-02-24 11:51:00 | citrate synthase and ACSS1 have tumorigenic functions in hepatocellular carcinoma | 27363021 |
| 2018-01-06 12:48:00 | Citrate synthase activity was lower in patients with heart failure with preserved ejection fraction compared to controls. | 27179829 |
| 2017-12-09 11:28:00 | mir-122 and its targets G6PC3, ALDOA and CS play roles in the hypoxia responses that regulate glucose and energy metabolism and can serve as hypoxia biomarkers. | 27793029 |
| 2017-11-04 13:11:00 | METTL12 methylates CS on Lys-395, which is localized in the CS active site. Interestingly, the METTL12-mediated methylation inhibited CS activity and was blocked by the CS substrate oxaloacetate. | 28887308 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CISY_HUMAN,
A0A024RB75_HUMAN
UniprotKB:
O75390,
A0A024RB75
UniParc:
UPI00000700D6
EMBL:
BT007414,
CH471054,
BC072016,
BC010106,
AF047042,
BC000105,
BX640838,
AK074956,
AF053631
Ensembl:
ENSG00000062485
KO:
hsa:1431
|
| Nucleutide sequences |
EMBL-CDS:
BAC11314.1,
AAH10106.1,
AAC25560.1,
AAP36082.1,
AAH72016.1,
CAE45911.1,
AAQ13428.1,
AAH00105.3,
EAW96924.1,
EAW96923.1
Gene_ORFName:
hCG_2016169
Ensembl_TRS:
ENST00000351328
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000342056
RefSeq:
NP_004068.2
|
| Others |
UniRef100:
UniRef100_O75390
UniRef90:
UniRef90_O75390
UniRef50:
UniRef50_O75390
UniGene:
Hs.743252
CCDS:
CCDS8913.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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