| Type | Description |
|---|---|
| Definition | NSF attachment protein alpha |
| Date | Results | Publications |
|---|---|---|
| 2016-08-13 10:14:00 | alphaSNAP expression showed no change in pilocarpine-induced epileptic rats in the acute phase, but in the chronic phase levels were lower. siRNA decreased the time of latency to seizure and increased the incidence of chronic idiopathic epilepsy seizures. | 26156199 |
| 2015-06-20 10:41:00 | In severe acute pancreatitis, downregulated expression of alphaSNAP in intestinal epithelial cells leads to reduced occludin expression, apoptosis of intestinal epithelial cells, and increased permeability of the intestinal barrier. | 25278303 |
| 2013-11-16 11:52:00 | a model of NSF-mediated disassembly in which the reaction is initiated by a 1:1 interaction between alpha-SNAP and the ternary SNARE complex, followed by NSF binding. | 23836889 |
| 2010-01-21 00:00:00 | alpha-SNAP inhibits exocytosis by binding to the syntaxin SNARE motif and in turn prevents SNARE assembly, revealing an unexpected site of action for alpha-SNAP in the SNARE cycle that drives exocytotic membrane fusion. | 18094056 |
| 2010-01-21 00:00:00 | A yeast two-hybrid screen using NSF as bait identified Rab11-FIP3 and the Pak-binding nucleotide exchange factor betaPIX as putative binding partners | 16795052 |
| Type | IDs |
|---|---|
| Synonymous | alpha-SNAP |
| Gene |
UniProtKB-ID:
SNAA_RAT
UniprotKB:
P54921
UniParc:
UPI0000135B0D
EMBL:
BC063156,
X89968
Ensembl:
ENSRNOG00000001494
KO:
rno:140673
|
| Nucleutide sequences |
EMBL-CDS:
AAH63156.1,
CAA62005.1
Ensembl_TRS:
ENSRNOT00000002044
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000002044
RefSeq:
XP_017444195.1,
NP_542152.1
|
| Others |
UniRef100:
UniRef100_P54921
UniRef90:
UniRef90_P54921
UniRef50:
UniRef50_P54921
UniGene:
Rn.31745
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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