| Type | Description |
|---|---|
| Definition | ankyrin repeat and SOCS box containing 8 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 10:44:00 | E3 ubiquitin ligase ankyrin repeat and SOCS box-containing 8(ASB8) interacted with TBK1/IKKi and phosphorylation modification of ASB8 at site of Ser17 to further strengthen its ubiquitination activity were verified. Phosphorylated ASB8 accelerates K48-linked ubiquitination and degradation of TBK1/IKKi, which further reduces phosphorylation level of IRF3 and inhibits production of IFN-beta. | 32298923 |
| 2010-01-21 00:00:00 | molecular cloning and characterization of the human ASB-8 gene | 12559969 |
| Type | IDs |
|---|---|
| Synonymous | PP14212 |
| Gene |
UniProtKB-ID:
ASB8_HUMAN,
F5GYF0_HUMAN
UniprotKB:
Q9H765,
F5GYF0
UniParc:
UPI000204AB25,
UPI00001260EB
EMBL:
AK289957,
BC001321,
AK024908,
AC074029,
AF464877
Ensembl:
ENSG00000177981
KO:
hsa:140461
|
| Nucleutide sequences |
EMBL-CDS:
AAH01321.1,
BAF82646.1,
AAQ04830.1,
BAB15033.1
Gene_ORFName:
PP14212
Ensembl_TRS:
ENST00000317697,
ENST00000536549,
ENST00000539528,
ENST00000536953,
ENST00000535055
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000445622,
ENSP00000320893,
ENSP00000438498,
ENSP00000440773,
ENSP00000445540
RefSeq:
NP_001306230.1,
NP_077000.1,
NP_001306225.1,
NP_001306229.1,
NP_001306227.1,
NP_001306226.1,
NP_001306228.1
|
| Others |
UniRef100:
UniRef100_Q9H765,
UniRef100_F5GYF0
UniRef90:
UniRef90_A0A4W2I5L7,
UniRef90_Q9H765
UniRef50:
UniRef50_A0A4W2I5L7,
UniRef50_Q9H765
UniGene:
Hs.432699
CCDS:
CCDS8761.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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