| Type | Description |
|---|---|
| Definition | CD200 receptor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-15 10:31:00 | Review of the CD200-CD200R axis, including the biology behind CD200-CD200R interaction and the role(s) it plays in tumor microenvironment and tumor growth, and activation/effector functions of T cells; discussion of CD200-CD200R's role as potential checkpoint molecules for cancer immunotherapy | 32030689 |
| 2018-06-09 10:42:00 | Reduced expression of monocyte CD200R is associated with enhanced proinflammatory cytokine production in sarcoidosis | 27929051 |
| 2018-03-31 10:43:00 | we demonstrated for the first time that CD200R is highly expressed on cells involved in type 2 immune responses, namely on Th2, Tc2, ILC2, and basophils. All these cell types play a role in type 2 inflammation. | 28106273 |
| 2018-03-24 11:45:00 | Residual CD200 activity may prevent completion of abortions via induction of Treg cells. In chronic histiocytic intervillositis, infiltrating maternal effector T cells may block Treg induction. An autocrine role for CD200-CD200R interaction versus inhibition of soluble CD200 by soluble CD200R is discussed. | 28326648 |
| 2017-12-30 10:44:00 | MMP12-producing monocyte-derived cells in gingival tissue of periodontitis patients also had reduced CD200R surface levels. Treatment with a CD200R ligand reduced CSF2-induced MMP12 production in these cells. This novel association of the CD200/CD200R pathway with MMP12 production by monocyte-derived cells may play a key role in PD progression. | 29101312 |
| Type | IDs |
|---|---|
| Synonymous | CD200R, HCRTR2, MOX2R, OX2R |
| Gene |
UniProtKB-ID:
MO2R1_HUMAN
UniprotKB:
Q8TD46
UniParc:
UPI000012F416,
UPI000002AE38,
UPI000002AE37,
UPI000002AE36
EMBL:
AF283760,
AK293071,
AK126349,
AF495380,
BC069721,
BC069661,
BC093890,
AF497550,
AF497548,
BC069743,
CH471052,
AY358910,
AY284975,
AC074044,
AF497549
Ensembl:
ENSG00000163606
KO:
hsa:131450
|
| Nucleutide sequences |
EMBL-CDS:
AAM14622.2,
AAH69661.1,
AAH69721.1,
AAQ89269.2,
BAG54311.1,
BAF85760.1,
EAW79658.1,
AAN61171.1,
AAM16159.2,
EAW79657.1,
AAH93890.1,
AAQ19772.1,
AAM16157.2,
AAM16158.2,
AAH69743.1
Gene_ORFName:
UNQ2522/PRO6015
Ensembl_TRS:
ENST00000490004,
ENST00000440122,
ENST00000471858,
ENST00000308611
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000418928,
ENSP00000405733,
ENSP00000311035,
ENSP00000418801
RefSeq:
NP_740750.1,
NP_620161.1,
NP_620386.1,
NP_620385.1
|
| Others |
UniRef100:
UniRef100_Q8TD46
UniRef90:
UniRef90_Q8TD46
UniRef50:
UniRef50_Q8TD46
UniGene:
Hs.309158
CCDS:
CCDS54623.1,
CCDS46889.1,
CCDS2970.1,
CCDS2969.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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