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13077 Cyp1a2

13077

Cyp1a2

cytochrome P450, family 1, subfamily a, polypeptide 2

protein-coding

Mus musculus

基因描述

Type Description
Definition cytochrome P450, family 1, subfamily a, polypeptide 2

研究结论

Date Results Publications
2019-07-20 11:19:00 Its mRNA expression is decreased by the high level of MRSA, but the low level of MRSA increased its expression. 30944282
2019-06-29 10:26:00 results demonstrate that 2,3,4',5-tetrahydroxystilbene-2-O-beta-D-glucoside enhances hepatic expression of CYP3A4, CYP2E1 and CYP1A2, and thus exacerbates the hepatotoxicity induced by acetaminophen in mice. 29184146
2018-10-20 11:17:00 Distribution of parent PCB congeners also varied by genotype with strikingly high levels of PCB 77 in poor-affinity Ahr (d) Cyp1a2(-/-) while Ahr (b) Cyp1a2(+/+) mice effectively sequestered coplanar PCBs in the liver. 29197979
2016-02-20 10:55:00 our results suggest a more important contribution of CYP1A2 to the in vivo plasma clearance and thus detoxification of 4-Aminobiphenyl 25922528
2016-02-06 11:27:00 hepatic CYP1A2 plays a critical role in the attenuation of hyperoxic lung injury by decreasing lipid peroxidation and oxidative stress in vivo. 25680282

名称对应

Type IDs
Synonymous CP12, CYPIA2, P450-3
Gene
UniProtKB-ID: CP1A2_MOUSE, B6VGH4_MOUSE
UniprotKB: P00186, B6VGH4
UniParc: UPI0000023A3C
EMBL: X04283, K02589, M10022, BC054827, X00479, X01682, FJ392393, BC018298
Ensembl: ENSMUSG00000032310
KO: mmu:13077
Nucleutide sequences
EMBL-CDS: CAA25156.1, AAA37509.1, AAH18298.1, CAA27832.1, CAA25837.1, AAA37508.1, AAH54827.1, ACJ12937.1
Ensembl_TRS: ENSMUST00000034860
Protein sequencees
Ensembl_PRO: ENSMUSP00000034860
RefSeq: NP_034123.1
Others
UniRef100: UniRef100_P00186
UniRef90: UniRef90_P00186
UniRef50: UniRef50_P00185
UniGene: Mm.15537
CCDS: CCDS23229.1

全选

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