| Type | Description |
|---|---|
| Definition | cytochrome P450, family 11, subfamily b, polypeptide 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-11 11:02:00 | The requirement of the adrenal clock to stabilize the circadian Glucocorticoid rhythm during exposure to aberrant Light-dark cycles was determined using novel aldosterone synthase (AS)Cre/+::Bmal1Fl/Fl mice in which Bmal1 deletion occurred during postnatal adrenal transdifferentiation. | 30321360 |
| 2016-06-11 11:36:00 | Aldosterone synthase knockout mouse shows odium-induced endothelial sodium channel up-regulation in vascular endothelium | 26324851 |
| 2016-05-21 10:25:00 | Aldosterone synthase (CYP11B2) is a key regulator of fibrotic remodeling during atrial fibrillation. | 26047574 |
| 2010-01-21 00:00:00 | Modest increase in aldosterone synthase (AS) expression makes blood pressure more sensitive to salt in mice, suggesting that genetically increased AS expression in humans may contribute to hypertension and cardiovascular complication with high-salt diets. | 18039983 |
| 2010-01-21 00:00:00 | Differential regulation of aldosterone synthase and 11beta-hydroxylase transcription by steroidogenic factor-1 | 11932209 |
| Type | IDs |
|---|---|
| Synonymous | Cpn2, Cyp11b, Cyp11b-2 |
| Gene |
UniProtKB-ID:
C11B2_MOUSE,
G3UWE4_MOUSE
UniprotKB:
P15539,
G3UWE4
UniParc:
UPI0001549F73,
UPI0000021F5E
EMBL:
J04451,
BC116908,
BC119321,
AC139671,
S85260
Ensembl:
ENSMUSG00000022589
KO:
mmu:13072
|
| Nucleutide sequences |
EMBL-CDS:
AAI16909.1,
AAA50299.1,
AAI19322.1,
AAB21517.2
Ensembl_TRS:
ENSMUST00000238900,
ENSMUST00000167634
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000158954,
ENSMUSP00000131503
RefSeq:
NP_034121.4
|
| Others |
UniRef100:
UniRef100_P15539
UniRef90:
UniRef90_P30099
UniRef50:
UniRef50_P30099
UniGene:
Mm.377079
CCDS:
CCDS27536.3
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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