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1306 COL15A1

1306

COL15A1

collagen type XV alpha 1 chain

protein-coding

Homo sapiens

基因描述

Type Description
Definition collagen type XV alpha 1 chain

研究结论

Date Results Publications
2019-01-26 11:16:00 This study identified collagen XV as a new low O2 tension sensitive gene, and provided a novel mechanistic evidence that directly HIF-1alpha (hypoxia-inducible factor-1 alpha) mediates collagen XV expression in response to hypoxia, since it was found specifically in vivo recruited at collagen XV promoter, in hypoxia-preconditioned mesenchymal stromal cells. 30537732
2016-12-17 11:14:00 COL15A1 mRNA was up-regulated in hepatocellular cancer (HCC) and collagen XV was expressed along the sinusoid-like endothelium of HCC but not in non-tumoral regions, which implies that collagen XV contributes to the capillarization of HCC. 26293333
2016-08-20 10:04:00 This study demonstrated that novel role for collagen XV in motor axon pathfinding and neuromuscular development. 26937007
2016-03-12 10:34:00 we identified an epithelial ovarian cancer susceptibility loci at 9q22.33 (rs1413299 in COL15A1, P(meta) = 1.88 x 10(-8)) 25134534
2015-01-03 10:58:00 The obtained results indicate that the changes in gene expression in bone marrow progenitor cells can be involved into space flight-induced osteopenia. 25509878

名称对应

Type IDs
Gene
UniProtKB-ID: COFA1_HUMAN, B3KTP7_HUMAN
UniprotKB: P39059, B3KTP7
UniParc: UPI0000211506, UPI0000372E5F
EMBL: AF052975, AF052958, AF052971, AF052966, AF052965, L25283, L25281, AF052974, AF052973, AF052964, L01697, D21230, AF052967, AF052956, AL354923, AK095885, L25284, AF052972, AF052970, AF052960, L25285, L25280, AF052969, AF052957, L25286, AF052961, AF052962, AF052968, AF052959, AL136084, L25282, AF052963
Ensembl: ENSG00000204291
KO: hsa:1306
Nucleutide sequences
EMBL-CDS: AAC78500.1, AAA58429.1, BAA04762.1, BAG53159.1
Ensembl_TRS: ENST00000375001
Protein sequencees
Ensembl_PRO: ENSP00000364140
RefSeq: NP_001846.3, XP_011516516.1
Others
UniRef100: UniRef100_B3KTP7, UniRef100_P39059
UniRef90: UniRef90_B3KTP7, UniRef90_P39059
UniRef50: UniRef50_P39059, UniRef50_L5M777
UniGene: Hs.409034
CCDS: CCDS35081.1

全选

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