| Type | Description |
|---|---|
| Definition | cathepsin C |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 11:36:00 | CTSC may promote macrophage towards M1 activation status through FAK-induced p38MAPK/NF-kappaB signaling pathway activation. | 31229505 |
| 2019-05-04 12:46:00 | Cathepsin C regulates neutrophil elastase activation and E-cadherin cleavage in acute pancreatitis. | 30455353 |
| 2019-04-20 12:00:00 | The data suggest that CatC promotes microglia M1 polarization and aggravates neuroinflammation via activation of Ca(2+)-dependent pathway. | 30651105 |
| 2017-05-07 00:47:00 | During the active remyelinating phase, both CysF knockdown (CysFKD) and microglial-selective CatC overexpression (CatCOE) showed a worsening of the demyelination in Plp(4e/-) transgenic mice. Conversely, during the chronic demyelinating phase, CatC knockdown (CatCKD) ameliorated the demyelination. Our results suggest that the balance between CatC and CysF expression controls the demyelination and remyelination process. | 28251676 |
| 2016-10-08 11:54:00 | Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases. | 26884336 |
| Type | IDs |
|---|---|
| Synonymous | AI047818, CatC, DPP1, DPPI |
| Gene |
UniProtKB-ID:
CATC_MOUSE,
Q3U7T5_MOUSE,
Q8BQL3_MOUSE,
Q3UBY5_MOUSE
UniprotKB:
P97821,
Q3U7T5,
Q8BQL3,
Q3UBY5
UniParc:
UPI00001A46D5,
UPI000002352A,
UPI00000EAF2B
EMBL:
AK049406,
AK150761,
AK146858,
AK152524,
BC067063,
AC124322,
U89269,
U74683
Ensembl:
ENSMUSG00000030560
KO:
mmu:13032
|
| Nucleutide sequences |
EMBL-CDS:
AAB49457.1,
AAH67063.1,
AAB58400.3,
BAE31284.1,
BAC33738.1,
BAE29829.1,
BAE27487.1
Ensembl_TRS:
ENSMUST00000032779,
ENSMUST00000131108
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000032779,
ENSMUSP00000147006
RefSeq:
NP_001298719.1,
XP_036008525.1,
NP_034112.3,
XP_006507383.1
|
| Others |
UniRef100:
UniRef100_Q8BQL3,
UniRef100_Q3U7T5,
UniRef100_P97821
UniRef90:
UniRef90_Q3U7T5,
UniRef90_P80067
UniRef50:
UniRef50_P53634,
UniRef50_P53634-3
UniGene:
Mm.322945
CCDS:
CCDS21438.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员